A Sertoli-Leydig Cell Tumor with Endometrial Hyperplasia in a Postmenopausal Woman

Sertoli-Leydig cell tumors (androblastomas) are sex-cord stroma-derived ovarian neoplasms and represent only 0.2% of all ovarian cancers. These tumors are almost always unilateral and occur most often in the third decade of life. Although many cases of Sertoli-Leydig cell tumor have been reported in the literature, incidental finding of this tumor without any clinical and laboratory evidence is rare. A well-differentiated Sertoli-Leydig cell tumor associated with endometrial hyperplasia detected during histopathologic examination of a hysterectomy and bilateral salpingo-oophorectomy specimen is reported, with a review of the recent literature.