Abstract
A
Abdominal and systemic inflammaton, with lysophosphatidic acid receptor 1 antagonist KI16425, associated with peritoneal sepsis, in mouse model, 60
Abdominal pain and heartburn, in teenager female, 50
Accelerated bone maturation, short stature, and early growth cessation, caused by heterozygous mutations in Aggrecan, 93
Acidic glycosaminoglycans interactions, with basic proteins and peptides, 18
Actin related protein 2/3 (Arp 2/3) complex, inhibits pulmonary endothelial barrier function and recovery, 63
Acute lung injury (ALI)
induced by LPS, with anti-inflammatory effects of C-ABL inhibition, 66
mediated by group V phospholipase A2 (gVPLA2), with hemin-induced in mice, 70
Acute myeloid leukemia (AML)
in association with paraneoplastic orthostatic hypotension and trisomy 8, 123
in association with translocation t(6;9) and FMS-like tyrosine kinase 3 gene (FLT3), 125
ceramide mediated lethal mitophagy, a novel cell death mechanism, in FLT3, 102
day of admission and clinical outcome in, 107
epidemiology and treatment outcomes, insured versus uninsured patients, 113
time from hospital admission to induction chemotherapy adversely affects outcomes in patients with, 108
Acute renal infarction, case studies, 137
Adiponectin expression, with weight gain versus obesity, asociated with leptin effects, 27
Adipose function and expansion, regulated by extracellular matrix (ECM), 31
Adipose-derived mesenchymal stem cells, associated with bleomycin-induced pulmonary fibrosis, in chronic mouse model, 71
Adrenal insufficiency, associated with cholestatic drug-induced liver injury (DILI), with treatment of corticosteroid, in patient with tuberculosis, 44
Age-associated autosomal loci, with epigenetic response, associated with high risk for metabolic syndrome, in Northern Europe, 89
Age-matched controls versus aromatase inhibitors, associated with falls and fractures, in breast cancer patients, 95
Aggrecan, caused short stature, accelerated bone maturation, and early growth cessation, with heterozygous mutations, 93
Aging drosophila, associated with effects of RPD3 mutation on mitochondrial function and metabolism, 92
Allergen-specific immunotherapy, for house dust mite-induced asthma, 83
Allogeneic hematopoietic cell transplantation, in humans, 101
Allogeneic stem cell transplant recepient, associated with invasive pulmonary aspergillosis, with CYP2C19*17 genetic polymorphism, 134
Alveolar hemorrhage, in crack cocaine smoker, with refractile foreign material deposits, 55
Amyloidosis, diagnosis using endoscopic-ultrasound guided celiac lymph node biopsy, 47
Anaplastic lymphoma kinase (ALK), receptors for midkine (MDK), activated by ethanol, in neuroblastoma cells and brain, 29
Aneurysms of the membranous septum (AMS) isolation, 20
Angiogenesis, associated with endothelial microRNA-130a, 15
Antiangiogenic effect, on cytotrophoblast cells, with urea and thiourea-based tipodal ligands, 12
Antiinflammatory and pro-inflammatory microglial phenotypes, associated with inhibition of Enhancer of Zeste Homologue 2 (Ezh2), 87
Appendicitis, in relation with appendix, 46
Appendix, cause of appendicitis, 46
Aromatase inhibitors
versus age-matched controls, associated with falls and fractures, in breast cancer patients, 95
in postmenopausal breast cancer patients, 100
Arsenic dysregulation, with transformation through accumulation of SQSTM1/P62, in human prostate stem/progenitor cell homeostasis, 114
Aspergillus tracheobronchitis (ATB), associated with systemic lupus erythematosus (SLE), 72
ATP sensitive potassium channel expression, in skeletal muscle, with energy consumption during physical activity, 28
Atrial fibrillation, followed catheter ablation of atrial flutter, by CHA2DS2VASC score, 17
Atrial flutter ablation, with atrial fibrillation prediction, by CHA2DS2VASC score, 17
Autoimmune encephalomyelitis, with commensal bacteria-derived lipid and increase in CD39+ Tregs, in patients with multiple sclerosis, 86
Autologous hematopoietic cell transplantation (AHCT), in light chain amyloidosis, using center for international blood and marrow transplant registry (CIBMTR) study, 96
B
Beta-cell cholecystokinin production, regulation by pancreatic islet GLP-1 secretion, in non-diabetic obesity, 26
Bleomycin-induced pulmonary fibrosis, associated with adipose-derived mesenchymal stem cells, in chronic mouse model, 71
B-natriuretic peptide (BNP), elevation induced by exercise, in patients with and without left ventricular hypertrophy, 7
Brain and neuroblastoma cells, with midkine (MDK) and ALK signaling, activated by ethanol, 29
Breast cancer
aromatase inhibitors versus age-matched controls, associated with falls and fractures in, 95
diet-induced obesity and angiogenesis, associated with identification of lipid lysophosphatidic acid signaling, 99
SIRT2 in regulating critical basal-like, determinant slug, 106
sphingosine kinases role in, 104
Bronchoalveolar lavage fluid cellularity, in association with cigarette smoke exposure, 61
C
C-ABL inhibition, in LPS-induced acute lung injury (ALI), with anti-inflammatory effects, 66
Carcinogenesis implications, in invasive breast cancer, 103
Cardiomyopathies, associated with cardiac inflammation increases with contractile dysfunction, caused by sarcomere protein mutation, 11
Cardiopulmonary bypass (CPB), associated with central airway obstruction, 77
Cardiotonic steroids-induced monolayer permeability, in lymphatic endothelial cell, attenuated by L-NAME, 13
CD39+ Tregs, with commensal bacteria-derived lipid, caused autoimmune encephalomyelitis, in multiple sclerosis, 86
Cell-free hemoglobin, HMOX1 and APOL1 in sickle cell nephropathy, 115
Cellular apoptosis, with NADPH-mediated stress, followed by blast-induced traumatic brain injury, 5
Central airway obstruction, associated with adjuvent cardio-pulmonary bypass (CPB), 77
Central retinal artery occlusion (CRAO), caused by familial thrombophilia, in young healthy females, 94
Central retinal vein thrombosis, associated with testosterone therapy, with unrecognized familial thrombophilia after 3, 3, and 4 months, in men, 98
Ceramide mediated lethal mitophagy, a novel cell death mechanism, in FLT3, 102
Cetuximab-induced aseptic meningitis, headache a case of, 120
Chinese herb-induced liver failure, from hemophagocytic lymphohistiocytosis, secondary to hepatosplenic T-cell lymphoma, 124
Chronic diarrhea, in relation with HIV, associated with spirochetes in gut, 45
Chronic kidney disease (CKD)
associated with medullary tophi, linking uric acid and progressive renal failure, 136
with improvement of quality-of-life, using custom web-based educational and monitoring platform, 38
Cigarette smoking
exposure on bronchoalveolar lavage fluid cellularity, 61
in human small airway epithelial cells, inhibited retinoic acid-inducible protein I (RIG-I), with interferon responses to influenza, 54
induce maladaptive apoptosis responses, in human bronchial epithelial cells, associated with COPD, 68
Cinobufotalin (CINO) inhibition, ovarian cancer cells proliferation, migration and invasion, 112
Clostridium difficile infection (CDI), diagnosed by loop-mediated isothermal amplification, 132
COPD, associated with cigarette smoke induced maladaptive apoptosis responses, in human bronchial epithelial cells, 68
Corticosteroid
induced morphological changes, in myeloid lineage cells, 116
treatment for cholestatic drug-induced liver injury (DILI), in patient with miliary tuberculosis and associated adrenal insufficiency, 44
Crack cocaine smoker, associated with alveolar hemorrhage, with refractile foreign material deposits, 55
Cyclooxygenase-2, in invasive breast cancer, 103
Cytotrophoblast cells, associated with urea and thiourea-based tipodal ligands, induced anti-angiogenic effect, 12
D
Deregulated cell cycle confers, resistance to aromatase inhibitors, in postmenopausal breast cancer patients, 100
Diabetes patients, associated with online discussion group for families, 39
Diet-induced obesity, angiogenesis and breast cancer progression, associated with identification of lipid lysophosphatidic acid signaling, 99
DNA damage, induced by oxidative stress and Forkhead box protein M1 (FOXM1) correlation, in human hepatocellular carcinoma (HCC), 43
Drug-induced liver injury (DILI), with treatment of corticosteroid, in patient with miliary tuberculosis, and associated adrenal insufficiency, 44
Dysautonomia, in patient with fulminant Guillain-Barre syndrome (GBS) mimicking brain death, 74
E
Early growth cessation, short stature and accelerated bone maturation, caused by heterozygous mutations in Aggrecan, 93
Eating disorders, caused elevated liver transaminases, 49
Elevated liver transaminase, causes of eating disorders, 49
End stage heart failure, and ventricular arrhythmias, associated with microRNA expression pattern, 2
Endoplasmic reticulum (ER) stress-related kidney diseases, associated with mesencephalic astrocyte-derived neurotrophic factor, as urine biomarker, 52
Endoscopic-ultrasound guided celiac lymph node biopsy, diagnosis for primary amyloidosis, 47
Endothelial cell CD36 transcription, associated with proangiogenic reprogramming, downregulated by LPA/PKD-1-HDAC7-FOXO1 signaling axis, 126
Endothelial mesenchymal transitions (ENDMT) and vascular permeability, in Kaposi's sarcoma-associated herpesvirus (KSHV) infected cells derived nanovesicles, 128
Endothelial microRNA-130a, associated with angiogenesis, 15
Enhancer of Zeste Homologue 2 (Ezh2) inhibition, reduces pro-inflammatory and increses antiinflammatory microglial phenotypes, 87
Escherichia coli, with interactions of usher-chaperone-subunit, during pilus biogenesis, 129
Excessive alcohol use, for screening in clinical practice, used in laboratory tests, 41
F
Factor V leiden (FVL) and prothrombin gene (PTG) heterozygosity, associated with ocular vascular occlusion (OVC) diagnostic ramifications, as first thrombotic event, 97
Familial thrombophilia, associated with central retinal artery occlusion (CRAO), in young healthy females, 94
Fatty acid synthase, cyclooxygenase-2 and osteoprtegerin expression, in invasive breast cancer, 103
FMS-like tyrosine kinase 3 gene (FLT3), associated with translocation t(6;9), in acute myelogenous leukemia (AML), 125
Focal segmental glomerulosclerosis (FSGS), associated with papillary renal cell carcinoma, 135
Forkhead box protein M1 (FOXM1), and correlation with DNA damage induced by oxidative stress, in human hepatocellular carcinoma (HCC), 43
FTY720 S-phosphonate, inactivation for GRK2-mediated S1PR1 phosphorylation and ubiquitiation, 62
Fulminant Guillain-Barre syndrome (GBS), associated with brain death due to dysautonomia, 74
Fulminant hepatic failure, from hemophagocytic lymphohistiocytosis, secondary to hepatosplenic T-cell lymphoma, 124
G
GCK-hyperglycemia (GCK-MODY), across racial/ethnic groups, using Exome Aggregation Consortium (EAC), 24
Gene expression and methylation status, in patient with maternal interstitial triplication of 15q11-q13 locus, 91
Genetic and epigenetic regulation, in pulmonary inflammation, for group V phospholipase A2, 59
Glucose tolerance, associated with fecal microbiota, in African-American male veterans, 32
Glycemic control, with impact of prostaglandin E2 (PGE2) levels, and therapeutic response in type 2 diabetes mellitus, 34
Glycogen synthase kinase 3β (GSK3β), regulated IL-33 receptor internalization and signaling, 57
Granulocytic dysplasia, associated with Pseudo-Pelger-Huët anomaly (PHA), in human granulocytic anaplasmosis (HGA), 122
GRK2-mediated S1PR1 phosphorylation and ubiquitiation, inactive with FTY720 S-phosphonate, 62
Group V phospholipase A2 (gVPLA2)
with genetic and epigenetic regulation, in pulmonary inflammation, 59
mediator of hemin-induced acute lung injury, in mice, 70
Growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis, in amplification of prostate stem/progenitor cells, 33
Growth hormone-releasing hormone receptors (GHRH-R) expression, in human papillary thyroid cancer cells, with effects on matrix metalloproteinase-2, 36
H
Headache, in association with cetuximab-induced aseptic meningitis, 120
Healthcare disparities, according to insurance status among patients with salivary gland tumors, 111
Heart rate variability, in women versus men, as marker of healthy longevity, 23
Heartburn and abdomnal pain, in teenager female, 50
Hemophagocytic lymphohistiocytosis (HLH)
associated with refractory anemia, with iron transfusion, 51
secondary to hepatosplenic T-cell lymphoma, mimicking chinese herb-induced liver failure, 124
Heparin-induced thrombocytopenia type II, 118
Hepatocellular carcinoma (HCC), associated with correlation of FOXM1, and oxidative stress induced DNA damage in human, 43
Hepatosplenic T-cell lymphoma, hemophagocytic lymphohistiocytosis, mimicking chinese herb-induced liver failure, 124
Herpes esophagitis, infection in immunocompetent teenager, 48
High-throughput genomics, response to histone deacetylase inhibitors, 110
Histone deacetylase inhibitors
regulation of inflammation and enhances Tregs, after allogeneic hematopoietic cell transplantation in humans, 101
using high-throughput genomics, predicting response to, 110
HMOX1 and APOL1, in sickle cell nephropathy, cell-free hemoglobin, 115
House dust mite
associated with pro-regulatory gut microorganisms and increases in pulmonary regulatory T cells, 84
induced asthma, treated with model of allergen-specific immunotherapy, 83
Human bronchial epithelial cells, cigarette smoke induce maladaptive apoptosis responses, associated with COPD, 68
Human granulocytic anaplasmosis (HGA), associated with Pseudo-Pelger-Huët anomaly (PHA) and granulocytic dysplasia, 122
Human lupus monocytes, with interferon signaling impact between monocyte subsets, with single cell gene expression, 82
4-Hydroxynonenal (4-HNE) modification, with TRPV1 residues, for channel activity preservation and microvascular function, 4
Hypercapnic respiratory failure management, in overlap syndrome, 75
Hyperglycemia, leads to hypertension in pregnancy, with stress and inflammatory signaling, 9
Hypertension
in pregnancy, due to stress and inflammatory signaling, induced by hyperglycemia, 9
pulmonary hypertension, pulmonary embolism, and renal artery stenosis, in patients with polythemia vera, 22
Hypoglycemia, in KCNJ11-related diabetes, treated with sulfonylurea, 35
Hypoxia-induced pulmonary hypertension
attenuated by smooth muscle cells, with deficiency of raptor, 16
prevention by inhibition of sphingosine kinase 1 (SphK1) and S1PR2, 6
Hypoxia-induced pulmonary vasoconstriciton, associated with voltage-gated Na+ channels, 69
I
IL-33 receptor internalization and IL-33 signaling, regulated by glycogen synthase kinase 3b (GSK3b), 57
Induction chemotherapy, adversely affects outcomes, in patients with acute myeloid leukemia, 108
Inflammation and enhances tregs, after allogeneic hematopoietic cell transplantation in humans, 101
Influenza
associated with pituitary tumor apoplexy, 37
with interferon responses, and retinoic acid-inducible protein I (RIG-I) inhibited by cigarette smoking, in human small airway epithelial cells, 54
Interferon beta/alpha ratio, predicts treatment response to tumor necrosis factor alpha inhibitoin, in rheumatoid arthritis, 81
Interferon signaling impact, in human lupus monocytes, between monocyte subsets, with single cell gene expression, 82
Interstitial triplication, associated with gene expression and methylation status, of 15q11-q13 locus, 91
Intranasal staphylococcal enterotoxin A, exposure to neutrophils and monocytes, with T cell-mediated systemic recruitment, 85
Invasive breast cancer, fatty acid synthase, cyclooxygenase-2 and osteoprtegerin expression, 103
K
Kaposi's sarcoma-associated herpesvirus (KSHV)
associated with lipoxins, 130
biology associated with lipoxins, 130
with nanovesicles associated with endothelial mesenchymal transitions (ENDMT) and vascular permeability, 128
KCNJ11-related diabetes, hypoglycemia treated with sulfonylurea, 35
Kruppel-like factor 2, associated with sphingosine 1-phosphate receptor 1 (S1PR1) and simvastatin, in human lung, 10
L
Left ventricular hypertrophy (LVH), with B-natriuretic peptide elevation induced by exercise, 7
Leptin effects, on adiponectin expression, with weight gain versus obesity, 27
Leukotriene A4 hydrolase (LTA4H) inhibitors, for primary effusion lymphoma (PEL), with chemotherapeutic modality, 131
Light chain amyloidosis, with autologous hematopoietic cell transplantation (AHCT) outcomes, using center for international blood and marrow transplant registry (CIBMTR) study, 96
Lipid lysophosphatidic acid signaling, identification for diet-induced obesity, angiogenesis and breast cancer progression, 99
Lipopolysaccharide (LPS)-induced lung injury, associated with sickle cell disease (SCD), versus ventilator-induced lung injury, in mice, 65
Loop-mediated isothermal amplification, for clostridium difficile infection (CDI) diagnosis, 132
LPA/PKD-1-HDAC7-FOXO1 signaling, regulates endothelial cell CD36 transcription, associated with proangiogenic reprogramming, 126
LPS-induced acute lung injury (ALI)
with anti-inflammatory effects of C-ABL inhibition, 66
associated with Parkin deficiency, 67
Lymph node histology, with evolution of peripherial blood smear, in miliary tuberculosis, 133
Lymphatic endothelial cell, with L-NAME attenuated cardiotonic steroids, induced by monolayer permeability, 13
Lysocardiolipin acyltransferase (LYCAT), with regulation of TGF-b-induced lung fibroblast differentiation, 58
Lysophosphatidic acid receptor 1 antagonist KI16425, associated with peritoneal sepsis, with abdominal and systemic inflammaton in mouse model, 60
M
Malignant salivary gland tumors, a single institution epidemiological report, 109
Mammalian target of rapamycin (mTOR) complexes 1 and 2, on myofibroblast differentiation, 79
Medullary tophi, associated with chronic kidney disease, linking uric acid and progressive renal failure, 136
Men versus women, with heart rate variability, as marker of healthy longevity, 23
Mesencephalic astrocyte-derived neurotrophic factor (MANF), for endoplasmic reticulum (ER) stress-related kidney diseases, as urine biomarker, 52
Metabolic syndrome, with epigenetic response of age-associated autosomal loci, in Northern Europe, 89
Metastatic glioblastoma, 76
Microbiota, associated with glucose tolerance, in African-American male veterans, 32
MicroRNA-130a, associated with angiogenesis, 15
Microvascular function, TRPV1 residues, with 4-hydroxynonenal (4-HNE) modification, for channel activity preservation, 4
Midkine (MDK) and ALK signaling, activated by ethanol, in neuroblastoma cells and brain, 29
Miliary tuberculosis (MTB), in association with peripherial blood smear evolution, and lymph node histology, 133
Mitochondrial function and metabolism, with effects of RPD3 mutation, in aging drosophila, 92
MRSA endocarditis, treated with veno-venous extracorporeal membrance oxygenation, 21
Multiple sclerosis, with commensal bacteria-derived lipid, caused autoimmune encephalomyelitis and increased in CD39+ Tregs, 86
Myeloid lineage, corticosteroid-induced, morphological changes in cells of, 116
Myocardial infarction, associated with stroke incidence, in psoriasis, 3
Myocardial ischemia, induced by vasodialator, using dual-energy CT myocardial perfusion imaging, 19
Myofibroblast differentiation, associated with mammalian target of rapamycin (mTOR) complexes 1 and 2, 79
N
NADPH oxidase expression, in association with oxidative stress reduces cell death, followed blast-induced traumatic brain injury, 5
Nanovesicles, with promotion of endothelial mesenchymal transitions (ENDMT) and vascular permeability, in Kaposi's sarcoma-associated herpesvirus (KSHV) infected cells, 128
Neuroblastoma cells and brain, with midkine (MDK) and ALK signaling, activated by ethanol, 29
Neurofibromatosis, associated with pulmonary embolism, 73
Neurulation and orofacial development, associated with gene regulatory network, 88
Neutrophils and monocytes, after intranasal staphylococcal enterotoxin A exposure, with T cell-mediated systemic recruitment, 85
Nondiabetic obesity, with regulation of pancreatic islet GLP-1 secretion, on beta-cell cholecystokinin production, 26
Nuclear factor (erythroid-derived 2)-like 2, associated with ventilatorinduced lung injury, 64
O
Obesity versus weight gain, with effects of leptin, on adiponectin expression, 27
Ocular vascular occlusion (OVC), diagnostic ramifications associated with factor V leiden (FVL) and prothrombin gene (PTG) heterozygosity, 97
Orofacial development and neurulation, associated with gene regulatory network, 88
Osteonecrosis development, with interaction of testosterone therapy and previously undiagnosed familial thrombophilia, 25
Osteoprtegerin expression, in invasive breast cancer, 103
Ovarian cancer cells proliferation, migration and invasion, inhibition of cinobufotalin, 112
Overlap syndrome, associated with presentation and management of hypercapnic respiratory failure management, 75
Oxidative stress
in association with NADPH oxidase expression, reduces cell death followed blast-induced traumatic brain injury, 5
induced DNA damage, and correlation of FOXM1, in human hepatocellular carcinoma (HCC), 43
P
Pancreatic islet GLP-1 secretion, regulates beta-cell cholecystokinin production, in non-diabetic obesity, 26
Pancreatico-pleural fistula (PPF), cause of recurrent pleural effusion, 78
Papillary renal cell carcinoma, associated with focal segmental glomerulosclerosis (FSGS), 135
Papillary thyroid cancer cells, with receptors for growth hormone-releasing hormone (GHRH-R) expression, on matrix metalloproteinase-2, 36
Paraneoplastic orthostatic hypotension, associated with trisomy 8, in acute myeloid leukemia, 123
Parkin deficiency, associated with LPS-induced acute lung injury, 67
Peripherial blood smear evolution, with lymph node histology, in miliary tuberculosis, 133
Peritoneal sepsis, associated with lysophosphatidic acid receptor 1 antagonist KI16425, with abdominal and systemic inflammaton in mouse model, 60
Physical activity, with ATP sensitive potassium channel expression, in skeletal muscle with energy consumption, 28
Pilus biogenesis, with usher-chaperone-subunit interactions, in Escherichia coli, 129
Pituitary tumor apoplexy, associated with influenza, 37
Platelet endothelial cell adhesion molecule 1 (PECAM1), induced by simvastatin, for endothelial barrier function, 80
Poly-L-lysine versus protamine effects, associated with prothrombin time, 42
Polythemia vera, associated with pulmonary hypertension, pulmonary embolism, hypertension and renal artery stenosis, 22
Postmenopausal breast cancer patients, deregulated cell cycle confers, resistance to aromatase inhibitors in, 100
Preeclampsia
impact on offspring health, 53
in pre-gestational diabetic pregnancy, in Bangladeshi patients, 30
Pregestational diabetic pregnancy, with prevalence of preeclampsia, in Bangladeshi patients, 30
Pregnancy, effect of vitamin D supplementation, on maternal and neonatal outcomes, using randomized clinical trials, 40
Primary cardiac prosthetic valve-associated lymphoma, case report and literature review, 117
Primary effusion lymphoma (PEL), associated with leukotriene A4 hydrolase (LTA4H) inhibitors, with chemotherapeutic modality, 131
Proangiogenic reprogramming, associated with endothelial cell CD36 transcription, downregulated by LPA/PKD-1-HDAC7-FOXO1 signaling axis, 126
Proinflammatory and antiinflammatory microglial phenotypes, associated with inhibition of Enhancer of Zeste Homologue 2 (Ezh2), 87
Proregulatory gut microorganisms, associated with house dust mite exposure, and increases in pulmonary regulatory T cells, 84
Prostaglandin E2 (PGE2), impact on glycemic control and therapeutic response in type 2 diabetes mellitus, 34
Prostate stem/progenitor cells amplification, associated with growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis, 33
Protamine versus poly-L-lysine effects, associated with prothrombin time, 42
Protein inhibitor of activated SATA1 (PIAS1) stability, in ubiquitinproteasome system, 56
Proteins and peptides, interactions with acidic glycosaminoglycans, 18
Prothrombin gene (PTG) heterozygosity and factor V leiden (FVL), associated with ocular vascular occlusion (OVC) diagnostic ramifications, as first thrombotic event, 97
Prothrombin time, associated with effects of protamine versus poly-L-lysine, 42
Pseudo-Pelger-Huët anomaly (PHA), in human granulocytic anaplasmosis (HGA), associated with granulocytic dysplasia, 122
Psoriasis, associated with low myocardial infarction and stroke incidence, in hispanic patients, 3
Pulmonary aspergillosis, associated with allogeneic stem cell transplant recepient, with CYP2C19*17 genetic polymorphism, 134
Pulmonary embolism
hypertension, pulmonary hypertension and renal artery stenosis, in patients with polythemia vera, 22
in patients with neurofibromatosis, 73
Pulmonary endothelial barrier function and recovery, with inhibition of actin related protein 2/3 (Arp 2/3) complex, 63
Pulmonary fibrosis, induced by bleomycin associated with adipose-derived mesenchymal stem cells, in chronic mouse model, 71
Pulmonary hypertension
with hypoxia prevented by sphingosine kinase 1 (SphK1) and S1PR2 inhibition, 6
induced by hypoxia, with raptor deficiency in smooth muscle cells, 16
pulmonary embolism, hypertension and renal artery stenosis, in patients with polythemia vera, 22
Pulmonary inflammation, genetic and epigenetic regulation, of group V phospholipase A2, 59
Pulmonary regulatory T cells, exposure to house dust mite, associated with pro-regulatory gut microorganisms, 84
Pulmonary vasoconstriciton, induced by hypoxia, associated with voltage-gated Na+ channels, 69
Q
Quality-of-life improvement, using custom web-based educational and monitoring platform, in chronic kidney disease (CKD), 38
R
Recurrent pleural effusion, associated with pancreatico-pleural fistula (PPF), 78
Red blood cells, store and release interleukin-33, 105
Refractory anemia, associated with hemophagocytic lymphohistiocytosis (HLH), with iron transfusion, 51
Renal artery stenosis, pulmonary hypertension, pulmonary embolism, and hypertension, in patients with polythemia vera, 22
Retinal artery occlusion, as a first thrombotic event associated with high factor VIII and low free proteins, 119
Retinoic acid-inducible protein I (RIG-I), inhibited by cigarette smoking, and interferon responses to influenza, in human small airway epithelial cells, 54
Rheumatoid arthritis, with baseline serum interferon beta/alpha ratio, response to tumor necrosis factor alpha inhibitoin, 81
Right ventricular outflow to aortic valve velocity ratio, for severe aortic stenosis, with relative dimensionless index, 8
RPD3 mutation effects, associated with aging drosophila, on mitochondrial function and metabolism, 92
S
Sarcomere protein mutation, causes of cardiomyopathies, associated with cardiac inflammation increases with contractile dysfunction, 11
Severe aortic stenosis, using right ventricular outflow to aortic valve velocity ratio, for relative dimensionless index, 8
Short stature, accelerated bone maturation, and early growth cessation, caused by heterozygous mutations in Aggrecan, 93
Sickle cell disease (SCD), associated with ventilator-induced lung injury versus LPS-induced lung injury, in mice, 65
Simvastatin
associated with sphingosine1-phosphate receptor 1, via kruppel-like factor 2, 10
induced PECAM1, for endothelial barrier function, 80
SIRT2, in regulating critical basal-like breast cancer determinant slug, 106
Smooth muscle cells, attenuated by hypoxia-induced pulmonary hypertension, with deficiency of raptor, 16
Sphingosine kinase 1 (SphK1) and S1PR2 inhibition, with prevention of hypoxia mediated pulmonary hypertension, 6
Sphingosine kinases, role in breast cancer cell, 104
Sphingosine 1-phosphate receptor 1 (S1PR1), with simvastatin regulates human lung, via kruppel-like factor 2, 10
Spirochetes in gut, associated with chronic diarrhea in relation with HIV, 45
SQSTM1/P62 accumulation, in arsenic dysregulation of human prostate stem/progenitor cell homeostasis, 114
Staphylococcal enterotoxin A (SEA), exposure to neutrophils and monocytes, with T cell-mediated systemic recruitment, 85
Stress and inflammatory signaling, induced by hyperglycemia, leads to hypertension in pregnancy, 9
Stroke, associated with incidence of myocardial infarction, in psoriasis, 3
Systemic and abdominal inflammaton, with lysophosphatidic acid receptor 1 antagonist KI16425, associated with peritoneal sepsis, in mouse model, 60
Systemic lupus erythematosus (SLE), associated with aspergillus tracheobronchitis (ATB), 72
T
Testosterone therapy
associated with central retinal vein thrombosis in men, with unrecognized familial thrombophilia, after 3, 3, and 4 months, 98
on development of osteonecrosis, interaction with previously undiagnosed familial thrombophilia, 25
TGF-β-induced lung fibroblast differentiation, regulated by lysocardiolipin acyltransferase (LYCAT), 58
Thrombocytosis, associated with tretinoin, 121
Thrombophilia, with interaction of testosterone therapy, on development of osteonecrosis, 25
Transcutaneous aortic valve replacement (TAVR), in non-academic community hospital, 14
Translocation t(6;9), associated with FMS-like tyrosine kinase 3 gene (FLT3), in acute myelogenous leukemia (AML), 125
Traumatic brain injury, NADPH-mediated stress, with cell death reduction followed by blast injury, 5
Tretinoin associated with thrombocytosis, 121
Trimester of pregnancy, retinal artery occlusion, as first thrombotic event associated with high factor VIII and low free proteins, 119
Trisomy 8, associated with paraneoplastic orthostatic hypotension, in acute myeloid leukemia, 123
TRPV1 residues, for channel activity preservation and microvascular function, with 4-hydroxynonenal (4-HNE) modification, 3
Tuberculosis, treatment of corticosteroid for cholestatic drug-induced liver injury (DILI), and associated adrenal insufficiency, 44
Tumor necrosis factor alpha inhibitoin, with baseline serum interferon beta/alpha ratio, response in rheumatoid arthritis, 81
Type 2 diabetes mellitus, with impact of prostaglandin E2 (PGE2) levels, on glycemic control, 34
U
Ubiquitinproteasome system, with regualtion of protein inhibitor of activated SATA1 (PIAS1) stability, 56
Urinary tract infections (UTI), associated with vancomycin-resistant enterococci (VRE), in Springfield Illinois, 127
Urine biomarker, as mesencephalic astrocyte-derived neurotrophic factor (MANF), for endoplasmic reticulum (ER) stress-related kidney diseases, 52
Usher-chaperone-subunit interactions, during pilus biogenesis, in Escherichia coli, 129
V
Vancomycin-resistant enterococci (VRE), associated with urinary tract infections (UTI), in Springfield Illinois, 127
Vascular permeability and endothelial mesenchymal transitions (ENDMT), in Kaposi's sarcoma-associated herpesvirus (KSHV) infected cells derived nanovesicles, 128
Vasodialator induced myocardial ischemia, using dual-energy CT myocardial perfusion imaging, 19
Venous thromboembolism, associated with liver eQTLS for warfarin dose response genes, among African Americans, 90
Veno-venous extracorporeal membrance oxygenation, treatment for severe MRSA endocarditis, 21
Ventilatorinduced lung injury (VILI), associated with nuclear factor (erythroid-derived 2)-like 2, 64
Ventilator-induced lung injury, associated with sickle cell disease (SCD), versus lipopolysaccharide (LPS)-induced lung injury, in mice, 65
Ventricular arrhythmias, and end stage heart failure, associated with microRNA expression pattern, 2
Vitamin D supplementation, effect on maternal and neonatal outcomes, during pregnancy, using randomized clinical trials, 40
W
Warfarin dose response, to venous thromboembolism, associated with liver eQTLS, among African Americans, 90
Weight gain versus obesity, with effects of leptin, on adiponectin expression, 27
Women versus men, with heart rate variability, as marker of healthy longevity, 23