Hemorrhagic complications from anticoagulants are common and may manifest in any part of the human body. Skin discoloration, pain, tenderness, and soft-tissue swelling may be the main clinical features. The authors present 3 extraordinary cases of brachial plexus neuropathy associated with anticoagulant-induced hemorrhage. The signs, symptoms, important differentials, and clinical treatment are described with regard to the pathologic anatomy.
References
1.
Kounis NG, Alexandridis T., Gogos CA: Calf haematoma masquerading as veno-occlusive disease during anticoagulation . Br J Clin Pract40:541-542, 1986.
2.
Kounis NG, Macauley MB, Ghorbal MS: Iliacus hematoma syndrome. Can Med Assoc J112:872-873, 1975.
De Castro CM , Hall RJ, Glasser SP: Salivary gland haemorrhage. An unusual complication of coumadin anticoagulation. Am Heart J50:675-676, 1970.
5.
Kent DC: Bleeding into pulmonary cyst associated with anticoagulant therapy. Am Rev Resp Dis92:108-109, 1965.
6.
McAlistair WH, Coehler PR: Haemorrhage into a pheochromocytoma in a patient on anticoagulants. J Can Assoc Radiol18:404-405, 1967.
7.
Revach M., Kabili S., Zemer D.: Massive sublingual hemorrhage due to Coumadin causing suffocation. Harefuah50:675-676, 1970.
8.
Nade S.: Acute urinary suppression presumed due to bilateral ureteric obstruction by blood clot. An unusual feature of anticoagulant therapy. Med J Aust1:378-379, 1972.
9.
Mastroianni PP , Roberts MP: Femoral neuropathy and retroperitoneal hemorrhage . Neurosurgery13:44-47, 1983.
10.
Forfar JC: A seven year analysis of haemorrhage in patients on long-term anticoagulant treatment. Br Heart J42:128-132, 1979.
11.
Peterson CE , Kwaan HC: Current concepts of Warfarin therapy. Arch Intern Med146:581-584, 1986.
