This project investigated the potential spread of cancer within the larynx by an analysis of the permeability and resistance of the subepithelial spaces. Permeation and diffusion of dye injections in the loose connective tissues below the epithelium was analyzed by histologic preparations in the sagittal plane. The margins of the infusion were identified grossly and microscopically, and the influence of the fibrous, elastic, and muscular components was analyzed with reference to the dispersion of the dyes. A close correlation between laboratory data from normal postmortem larynges and clinical problems of laryngeal cancer was observed in this study.
AlonsoJM. Conservative surgery of cancer of the larynx. Trans Am Acad Ophthalmol Otolaryngol1947; 51: 633–42
2.
SomML. Surgical treatment of carcinoma of the epiglottis by lateral pharyngotomy. Trans Am Acad Ophthalmol Otolaryngol1959; 63: 28–49
3.
SomML. Conservative surgery for carcinoma of the supraglottis. J Laryngol Otol1970; 84: 655–78
4.
OguraJH. Supraglottic subtotal laryngectomy and radical neck dissection for carcinomas of the epiglottis. Laryngoscope1958; 68: 983–1003
5.
OguraJHSessionsDGSpectorGJ. Conservation surgery for epidermoid carcinoma of the supraglottic larynx. Laryngoscope1975; 85: 1808–15
6.
OguraJHSpectorGJSessionsDG. Conservation surgery for epidermoid carcinoma of the marginal area: Aryepiglottic fold extension. Laryngoscope1975; 85: 1801–7
7.
OguraJHBitterHF. Conservative surgery in cancer of the head and neck. Otolaryngol Clin North Am1969; 3: 641–65
8.
BoccaEPignataroOMosciaroO. Supraglottic surgery of the larynx. Ann Otol Rhinol Laryngol1968; 77: 1005–26
9.
NorrisCM. Technique of extended fronto-lateral partial laryngectomy. Laryngoscope1958; 68: 1240–50
10.
TuckerGF. Human larynx, coronal section atlas. Washington, DC: Armed Forces Institute of Pathology, 1971.
11.
Leroux-RobertJ. Les epitheliomas intra-larynges. Paris: Doin, 1936.
12.
LedererFL. Diseases of the ear, nose, and throat. Philadelphia: FA Davis Co, 1938.
13.
KernanJD. The pathology of carcinomas of the larynx studied in serial sections. Trans Am Acad Ophthalmol Otolaryngol1950; 55: 10–21
14.
BroylesEN. The anterior commissure tendon. Ann Otol Rhinol Laryngol1943; 52: 342–5
15.
KelemenGSadéJ. The vocal organs of the howling monkey. J Morphol1960; 107: 123–40
16.
WelshLWWelshJJRizzoTAJr.. Laryngeal spaces and lymphatics: Current anatomic concepts. Ann Otol Rhinol Laryngol1983; 92(suppl 105): 19–31
17.
MorgagniJB. The seats and causes of disease, investigated by anatomy. AlexanderB, trans. New York: Academy of Medicine, Hafner Publishing Co, 1960.
PressmanJJDowdyALibbyM. Further studies upon the submucosal compartments and lymphatics of the larynx by the injection of dyes and radioisotopes. Ann Otol Rhinol Laryngol1956; 65: 963–80
20.
WelshLWWelshJJ. The cervical lymphatics, human in vivo studies. Ann Otol Rhinol Laryngol1963; 72: 324–37
21.
WelshLW. The normal human laryngeal lymphatics. Ann Otol Rhinol Laryngol1964; 73: 569–84
