A fulminating fatal case of Henoch- Schöenlein purpura is reported along with a review of the basic disease. Death was due to hemorrhage and necrosis in volving the entire gastro-intestinal tract. To the authors' knowledge, death due to total intestinal infarction in this disease has not been previously described. Addi tional autopsy findings included a necro tizing vasculitis involving skin, lungs and gastro-intestinal tract as well as focal necrosis of the liver and adrenal glands and a membranous glomerulonephritis.
References
1.
Alexander, H.L. and Eyermann, C.H.: Food allergy in Henoch's purpura . Arch. Dermat. Syph.16: 322, 1927.
2.
Allen, D.M., Diamond, L.K. and Howell, D.A.: Anaphylactoid purpura in children (Schoenlein-Henoch syndrome)—review with a follow-up of the renal complications. Amer. J. Dis. Child.99: 833, 1960.
3.
Burke, D.M. and Jellinek, H.H.: Nearly fatal case of Schoenlein-Henoch syndrome following insect bite . Amer. J. Dis. Child.88: 772, 1954.
4.
Creger, W.P. and Houseworth, J.H.: Erythrophagocytosis and thrombocytopathy occurring during the course of a Henoch-Schoenlein purpura due to quinine . Amer. J. Med.17: 423, 1954.
5.
Davis, E.: The Schoenlein-Henoch syndrome of vascular purpura. Blood3: 129, 1948.
6.
Gairdner, D. : The Schoenlein-Henoch syndrome (anaphylactoid purpura). Quart. J. Med.17: 95, 1948.
7.
Henoch, E.: Uber Eine Eigenthumliche Form Von Purpura. Beal Khin. Wehschr.11: 641, 1874.
8.
Kreidberg, M.D. , Domeshek. W. and Lutorraca, R.: Acute vascular (Schoenlein-Henoch) purpura —an immunologic disease? New Eng. J. Med.253: 1014, 1955 .
9.
Krjukoff, A.N. and Agamaloff, K.: Problema septum complexa Henocha vo unutrennei patologie. Therap. Arch.18: 542, 1940.
10.
Levitt, J.M. and Burbank, B.: Glomerulonephritis as a complication of the Schoenlein-Henoch syndrome. New Eng. J. Med.248: 532, 1953.
11.
Lewis, I.C. : The Schoenlein-Henoch syndrome (anaphylactoid purpura) compared with certain features of nephritis and rheumatism. Arch. Dis. Child.30: 212, 1955.
12.
Lucutier, M.A. : A case of the Schoenlein-Henoch syndrome with myocardial necrosis. J. Clin. Path.5: 336, 1952.
13.
Muldoon, J.P. , Berg, A.M. and Kinnard, D.W.: Surgical implications of nonthrombocytopenic purpura. Ann. Surg.142: 817, 1955.
14.
Norkin, S. and Wiener, J.: Henoch-Schoenlein syndrome. Review of pathology and report of two cases. Amer. J. Clin. Path.33: 55, 1960.
15.
Osler, W.: On the surgical importance of the visceral crisis in the erythemic group of skin disease. Amer. J. Med. Sci.127: 751, 1904 .
16.
Osler, W.: The visceral lesions of purpura and allied conditions. Brit. Med. J.1: 617, 1914.
17.
Panos, T.C.: In Mesenchymal Diseases in Childhood, Report of Twenty-second Ross Pediatric Research Conference, Columbus, Ross Laboratories, 1957, p. 88.
Philpott, M.G. : The Schoenlein-Henoch syndrome in childhood with particular reference to the occurrence of nephritis. Arch. Dis. Child.27: 480, 1952.
20.
Poindexter, M.H., Pray, L.G. and Le Bien W.E. ,Purpura in childhood . Lancet77: 193, 1957.
21.
Schöenlein, J.L.: Allgemeine und Specialle Pathologie und Therapie, Freyburg2: 48, 1837.
22.
Seigel, J.J. , Brown, H.E. and Di Leo L.W.Purpura as a result of insect allergy: treatment with cortisone. Postgrad. Med.15: 46, 1954.
23.
Turin, R.D. , Mandel, S. and Hornstein, L.: Fulminating purpura with gangrene of lower extremity necessitating amputation. J. Pediat.54: 206, 1959.
24.
Wedgewood, R.J.P. and Klaus, M.H.: Anaphylactoid purpura: a long term follow-up study with special reference to renal involvement. Pediatrics16: 196, 1955.
25.
Wolfsohn, H. : Purpura and intussusception. Arch. Dis. Child.22: 242, 1947.
