Abstract

Spirituality and Religion
Spirituality is a multidimensional construct characterised by the individual search for connection beyond the immediate self, the pursuit of higher purposes, and the search for meaning in life, fostering personal growth, emotional regulation, resilience, and an intimate sense of transcendence (Bailey et al., 2025). While it may overlap with religion, the two constructs are not synonymous (Lucchetti et al., 2015). Religion typically provides structured and institutionalised guidance through shared doctrines, formal rituals, moral codes, and communal worship, thereby shaping spiritual development and promoting social cohesion, behavioural regulation, and moral conditioning (Dubey et al., 2025). Spirituality is primarily an individual, subjective, and experiential pathway oriented towards well-being, meaning making, and openness towards others and society, regardless of whether it is practiced within a religious framework (Dubey et al., 2025; Paul Victor & Treschuk, 2020). Thus, both constructs can contribute to emotional and social resilience (Schwalm et al., 2022), albeit religion through communal support and normative guidance, and spirituality through personal insight and transcendent experiences. Spirituality and religion are overlapping but non-isomorphic constructs, both socially and culturally embedded (Dy-Liacco et al., 2009). They are fundamental in understanding the multifaceted psychological dimensions of others, appreciating their suffering, and mobilising personal resources within the context of care, as well as in fostering resilience strategies within a person-centred approach.
Socio-Cultural Aspects of Spirituality
While spirituality is often conceptualised as an individual, subjective, and experiential pursuit, the ways in which individuals may construct models of spirituality and express it are profoundly influenced by their cultural, religious, and traditional values of the societies in which they live. In fact, cultural narratives provide symbolic elements influencing beliefs about transcendence, the meaning of human-being and suffering, shaping the content and expression of spiritual experiences.
Primary microsocial and broader social structures also influence individual spiritual development. Families serve as the primary container, as well as a vector, for educational, cultural, spiritual, and religious values, often transmitted through familial traditions and across generations (Körün & Satıcı, 2025). Early exposure to stress or, conversely, to a well-regulated and emotionally supportive family environment can profoundly shape emotional and behavioural development, and the underlying neurobiological architecture, as discussed below (Ventriglio et al., 2015). The family system also plays as a foundational framework for shaping personal beliefs, values, and moral principles (Raesi et al., 2025). For instance, infant baptism is practiced in several Christian traditions, including Catholicism, Eastern Orthodoxy, and certain Lutheran and Anglican communities, administered before the child can make a conscious decision. It acts as a conduit for grace, initiating the child into the faith while parents and godparents undertake the spiritual responsibility until the child can decide personally (Crisp, 2022).
Schools and peer networks may also serve as vectors for spiritual, behavioural models, and inspiration, particularly when educational or youth groups are guided by religious principles or when the communities they engage with are explicitly religious contexts, such as oratories, parishes, prayer groups, congregations, mosques, synagogues, temples, etc. (Heredia et al., 2020). Within these specific settings, institutionalised practices can be transmitted, spiritual norms reinforced, guidance provided, coping strategies modelled, and moral as well as prosocial behaviours strengthened.
Considering cultural and social factors in the clinical setting may also involve assessing the individual religious and spiritual orientations, with the aim of understanding, within a person-centred approach, their explanatory models of well-being and illness, experiences of suffering, and pathways of resilience. Culture is closely linked to the way mental illness is experienced, and spiritual factors can play a central role in the relationship between the individual cultural background and the understanding of illness experience (Nwokoroku et al., 2022). In fact, culture may play pathogenic effects, directly contributing to the emergence of symptoms (e.g. cultural conflicts or cultural bereavement in migrants or minority groups), and pathoselective effects, influencing the vulnerability of specific populations (e.g. minorities experiencing cultural conflicts within a broader society; Bhugra et al., 2021; Ventriglio et al., 2023). Cultural factors can also exert pathoplastic influences, modifying symptom presentation according to cultural models, symbolic frameworks, or socially shared meanings, as well as pathoelaborating effects, shaping how symptoms are managed and interpreted in relation to culturally grounded understandings of illness and healing. Additionally, culture can be pathoreactive, resulting in secondary modifications of values, beliefs about illness, and the ways individuals respond to symptoms following the experience of illness itself (Ventriglio et al., 2023). Collectively, these mechanisms illustrate the complex interplay between cultural context and psychopathological processes.
Culturally sensitive mental health interventions that consider patients’ spirituality and religious beliefs can substantially foster holistic, person-centred care, enhance psychological well-being, facilitate illness acceptance, and nurture personal hope (Olotu, 2023).
Neurobiology and Spirituality
Spirituality and religion are based on a complex interplay of cognitive control, affective valuation, reward circuitry, and self-referential networks, all elements of a neurobiological substrate for both the inner and motivational dimensions of spiritual experiences (Rim et al., 2019). Religious cognition often engages normative belief systems, social cognitive processes, and rule-based moral reasoning, involving a network of brain regions regulating cognitive, affective, and reward processes. Prefrontal and parietal areas, including the ventromedial prefrontal cortex and frontal–parietal areas, are involved in self-representation, attention, and moral reasoning (Rosmarin et al., 2022). Spiritual experiences and devotional practices are also associated with affective salience, self-transcendence, and altered states of consciousness, including modulation of limbic, paralimbic, and default mode networks. The recruitment of the reward system is involved, particularly the nucleus accumbens and prefrontal cortex, suggesting that religious and spiritual engagement can elicit reinforcement and affective salience comparable to other rewarding behaviours (Rosmarin et al., 2022). It is plausible that the periaqueductal grey contributes to affective regulation, altruistic behaviour, and the subjective experience of transcendence, while regions such as the inferior parietal lobule, medial thalamus, and caudate support self–other processing and the perceptual aspects of spiritual experiences (Rim et al., 2019). Interactions with the default mode network, anterior cingulate cortex, and medial prefrontal cortex likely facilitate higher-order processes such as perspective-taking, social cognition, and the maintenance of spiritual beliefs (Rosmarin et al., 2022).
Inner Serenity and Social Connectedness
Religious and spiritual traditions promote inner serenity and social connectedness, both essential dimensions for personal growth, respect for others, individual, and collective resilience. In Buddhism, particularly Mahāyāna, inner development (bhāvanā; Sanskrit: “development, cultivation”) is inseparable from compassion (karuṇā) and wisdom (prajñā). The doctrine of pratītyasamutpāda, or “dependent origination,” emphasises the relational nature of the self, establishing that no being exists in isolation. Spiritual practice fosters empathy, emotional regulation, and collective responsibility, while the bodhisattva (Sanskrit: bodhi = awakening, sattva = being) ideal directs practitioners towards the liberation of all beings, integrating inner serenity with active social engagement (Wang, 2025). In Hinduism, especially in Vedānta and the Bhagavad Gītā, inner realisation (mokṣa) is coupled with ethical action in the world (karma yoga). The cosmos is seen as a manifestation of Brahman (ultimate, unchanging, and infinite reality), and righteous action (dharma) is always embedded in relational networks. Spiritual maturity does not lead to withdrawal but encourages selfless action for the benefit of the cosmic and social order, fostering both serenity and social responsibility (Munshi & Bhagwan, 2025). Taoism emphasises harmony between the individual, nature, and community. Through the cultivation of spontaneity (ziran) and non-forcing (wu wei), practitioners align with natural rhythms, achieving inner balance. Social and environmental harmony emerge naturally from this individual-centred cultivation, highlighting a model in which psychological health is part of the ecological and communal health (Yip, 2004). Judaism is inherently relational and communal. Inner growth occurs through teshuvah (ethical return or repentance), while the human is seen as the custodian of the world (tikkun olam). Connection with God is realised through responsibility towards others, reinforcing social cohesion alongside personal moral development (Krumrei et al., 2013). In Islam, particularly Sufi traditions, spiritual cultivation (tazkiyat al-nafs, purification of the self) promotes universal love and service. The human being is a responsible custodian (khalīfa) of creation, and the natural world is a sign (āyah) of God (Zahir & Qoronfleh, 2025). Authentic spirituality is inseparable from compassion, equity, and communal responsibility, linking inner serenity with socially oriented ethical actions. Indigenous and animistic traditions (e.g. Amerindian, African, and Oceanic) conceptualise the self as intrinsically ecological and relational. Identity is defined through relationships with peers, ancestors, and territory. Creation is understood as an animate and relational resource (Cianconi et al., 2019). Ritual cohesion and collective responsibility promote high levels of communal resilience, demonstrating that spiritual and social dimensions are mutually reinforcing. Franciscan spirituality, a distinctive expression of Christian spirituality established by Saint Francis of Assisi (Italy), articulates a relational ontology grounded in brotherhood (fraternitas) and a symmetric engagement with creation. Within this framework, all beings, human and nonhuman, share inherent dignity, fostering both equality and relational humility. The Canticle of the Creatures (Laudato si’) presents a vision of the cosmos in which humans, animals, and elements are understood as all God’s creatures, siblings, reinforcing social and ecological connectedness. From a psychosocial perspective, this approach strengthens bonding and bridging social capital, enhances collective efficacy and resilience, and provides ethical frameworks that support adaptive coping in contexts of social, environmental, or ecological stress (Büssing et al., 2018). According to these models of spirituality, inner serenity is cultivated through compassion, ethical actions, and alignment with broader cosmic or social orders. Social connectedness is emphasised and ruled by relational ethics and responsibility towards others. These models not only support subjective well-being and emotional regulation but also strengthen social connectedness and collective resilience. Thus, the spiritual and social dimensions of human life are deeply interconnected and may constitute indispensable resources for a society characterised by health-promoting interactions and enhanced social resilience (Ventriglio et al., 2025).
Spirituality, Personal, and Social Resilience
Individual spirituality is a fundamental resource for promoting mental health, at the individual level as well as in the quality of social relationships (Long et al., 2024). Spirituality fosters inner serenity, coherence, and behavioural and emotional regulation, providing a coherent framework of values and experiences through which individuals can integrate the experience of illness in a resilient manner.
In the therapeutic psychiatric context, these dimensions are particularly relevant for person-centred and recovery-oriented approaches. Treatments should not be limited to symptom reduction or functional rehabilitation but extend to the reconstruction of personal experience, the cultivation of hope, and the narrative reinterpretation of suffering as a biographical experience. By supporting a coherent sense of self and facilitating processes of reflection, spirituality enhances resilience at both the personal and relational levels, enabling patients to engage in health-promoting social interactions and contribute to collective well-being. Incorporating assessments of spiritual orientation and personal meaning into clinical practice allows mental health professionals to tailor interventions that align with patients’ values, strengthen coping capacities, and reinforce social support networks. Ultimately, the integration of spiritual resources into recovery-oriented care fosters a holistic model of healing. It is essential to consider the inseparable link between the restoration of the self, the reestablishment of meaningful social bonds, and the promotion of sustained individual and social resilience.
Footnotes
Funding
The authors received no financial support for the research, authorship, and/or publication of this article.
Declaration of Conflicting Interests
The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
