Histologic sections of 15 biopsy samples of normal oral mucosa and 8 biopsy samples of malignant oral carcinoma from patients with A, B, or AB blood groups were treated with anti-A or anti-B human antiserum and then with fluorescein isothiocyanate-bound goat antihuman globulin. Normal cells fluoresced intensely. Fluorescence of malignant cells was diminished or lost.
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