Utilizing a blood-based medium, we determined the minimum inhibitory concentrations (MIC's) to sodium fluoride (NaF) of 45 bacterial strains representing 22 oral species. Bacterial susceptibility ranged from 128 μg/ml to 2048 μg/ml. Of those organisms tested, Actinobacillus actinomycetemcomitans, Capnocytophaga sputigena, Capnocytophaga gingivalis, Capnocytophaga ochracea, and Actinomyces viscosus were susceptible at lower levels of NaF.
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