Dissolution tests were conducted with human enamel following treatment with aqueous aluminum (Al) solutions under conditions of varying pH, concentration, and treatment time. Al reduced enamel dissolution in a pH 4 acetate buffer most effectively when used in the pH range of 3 to 4, at concentrations above 0.005 mollL, and for treatment times of more than four minutes. However, significant activity was observed with concentrations as low as 0.0005 mol/L Al and treatment times as short as 15 seconds. The effects of Al solution pH and concentration on enamel dissolution were related to the hydrolysis of Al above pH 4 and to the accelerated dissolution of apatite below pH 3.
References
1.
Adler, P. and Csoban, G. (1948): Protektiv Hatasok a Fogzomanc Oldópásánál, Fogorvosi Szemle Foszac41:327-329.
2.
Dezelic, N.; Bilinski, H.; and Wolf, R.H.H. (1971): Precipitation and Hydrolysis of Metallic Ions. IV. Studies on the Solubility of Aluminum Hydroxide in Aqueous Solution, J Inorg Nucl Chem33:791-798.
3.
Kleber, C.J. and Putt, M.S. (1984): Aluminum and Dental Caries : A Review of the Literature , Clin Prev Dent6(6):14-25.
4.
Kleber, C.J. and Putt, M.S. (1985): Uptake and Retention of Aluminum by Dental Enamel , J Dent Res64:1374-1376.
5.
Manly, R.S. and Bibby, B.G. (1949): Substances Capable of Decreasing the Acid Solubility of Tooth Enamel, J Dent Res28 :160-171.
6.
Muhlemann, H.R. and Regolati, B. (1974): IV. Aluminum- A Cariostatic Agent? In: Forum Medici, Nyon, Switzerland: Zyma Publishers, pp. 51-58.
7.
Putt, M.S. and Kleber, C.J. (1985): Dissolution Studies of Human Enamel Treated with Aluminum Solutions, J Dent Res64 :437-440.
8.
Regolati, B. (1970): A Factorial Study on the Cariostatic Effects of Aluminum and Fluoride. Thesis, University of Zurich, Switzerland, pp. 1-27.
9.
Regolati, B.; Schait, A.; Schmid, R.; Marthaler, T.M.; and Muhlemann, H.R. (1969): Effects of Aluminum and Fluoride on Caries, Fluorine Content, and Dissolution of Rat Molars, Helv Odont Acta13:59-64.
10.
Regolati, B.; Schait, A.; Schmid, R.; and Mühlemann, H.R. (1974): The Effect of Titanium, Aluminum, and Fluoride on Rat Caries, Helv Odont Acta18:92-96.
