The development of a novel flow-based, three-dimensional human blood–brain barrier model for studying brain infections is now under way
References
1.
AbbottN.J., PatabendigeA.A.K., DolmanD.E.M., YusofS.R., & BegleyD.J. (2010). Structure and function of the blood–brain barrier. Neurobiology of Disease37, 13–25.
2.
HawkinsB.T., & DavisT.P. (2005). The blood-brain barrier/neurovascular unit in health and disease. Pharmacological Reviews57, 173–185.
3.
PatabendigeA. (2012). The value of in vitro models of the blood–brain barrier and their uses. ATLA [In press.]
4.
PatabendigeA., SkinnerR.A., & AbbottN.J. (2012). Establishment of a simplified in vitro porcine blood–brain barrier model with high transendothelial electrical resistance. Brain Research [In press.] http://dx.doi.org/10.1016/j.brainres.2012.06.057.
5.
WaltersE.M., AgcaY., GanjamV., & EvansT. (2011). Animal models got you puzzled?: Think pig. Annals of the New York Academy of Sciences1245, 63–64.
6.
JanigroD., LeamanS.M., & StannessK.A. (1999). Dynamic in vitro modeling of the blood-brain barrier: A novel tool for studies of drug delivery to the brain. Pharmaceutical Science & Technology Today2, 7–12.
