Sulla Importanza Dell'Idiotipo Nell'Eziopatogenesi Delle Neoplasie Maligne Del Laringe: Nota I - Rilievi statistici sull'associazione delta manifestazione neoplastica con alcuni fattori ambientali

Sigarette smoke and alcohol have already been claimed to be possible determining factors of cancer of the respiratory apparatus. This work is but a small contribution to the problem of the role that the aforesaid substances may have in the development of larynx cancer. The analysis of the data, obtained through an accurate questioning of 137 individuals affected with cancer of the larynx and 137 controls with the same age and occupation, shows 1) that the incidence of smokers, who have been smoking more than 10 sigarettes pro die for at least ten years, is significantly greater in the first group; 2) that in the same group the incidence of people, who were using more than 1 liter of wine pro die for at least ten years, is higher — but not significatly — than in the control group. Therefore it may be concluded that there is a statistical association between the cancer of larynx and use of sigarettes.