Re the article “Is antipsychotic augmentation associated with improved functioning in patients on clozapine?” by Cho, Mukherjee and Sazhin.1 This was a very interesting article and, along with other recent publications,2,3 indicates that careful combination of two antipsychotic drugs can sometimes be more beneficial than monotherapy.
It would be very useful to know which drugs were used to augment, the number of patients on each drug, and the dose range—a table might be good?
Footnotes
ORCID iD
Cherrie Galletly
References
1.
ChoJHMukherjeeHSazhinV. Is antipsychotic augmentation associated with improved functioning in patients on clozapine?Australas Psychiatry2024; 32: 186–191.
2.
TaipaleHTanskanenATiihonenJ. Safety of antipsychotic polypharmacy versus monotherapy in a nationwide cohort of 61,889 patients with schizophrenia. Am J Psychiatr2023; 180: 377–385.
3.
TiihonenJTaipaleHMehtäläJ, et al.Association of antipsychotic polypharmacy vs monotherapy with psychiatric rehospitalization among adults with schizophrenia. JAMA Psychiatry2019; 76: 499–507.
