Pharmacodynamics of Nondepolarizing Muscle Relaxants

Abstract

References

Scott Rpf : Autonomic and cardiovascular effects of neuromuscular blocking drugs. Curr Opin Anaesthesiol 5:568-571, 1992

Scott Rpf , Belmont MR , Savarese JJ : Cardiovascular and autonomic effects of neuromuscular blocking drugs, in Kaplan J (ed): Cardiac Anesthesia . Philadelphia, PA, Grune & Stratton, 1992

Marshall RJ : Cardiovascular effects of neuromuscular blocking drugs. Curr Opin Anaesthesiol 4:599-602, 1991

Hughes R. , Chapple DJ : Cardiovascular and neuromuscular effects of dimethyl tubocurarine in anaesthetized cats and rhesus monkeys. Br J Anaesth 48:847-852, 1976

Hughes R. , Chapple DJ : Effects of non-depolarizing neuromuscular blocking agents on peripheral autonomic mechanisms in cats. Br J Anaesth 48:59-68, 1976

Savarese JJ : The autonomic margins of safety of metocurine and d-tubocurarine in the cat . Anesthesiology 50:40-46, 1979

Basta SJ : Modulation of histamine release by neuromuscular-blocking drugs. Curr Opin Anaesthesiol 5:572-576, 1992

Dyer J. , Warren K. , Merlin S. , et al: Measurement of plasma histamine: Description of an improved method and normal values. J Allergy Clin Immunol 70:82-87, 1982

Moss J. , Rosow CE : Histamine release by narcotics and muscle relaxants in humans. Anesthesiology 59:330-339, 1983

10.

Basta SJ , Savarese JJ , Ali HH , et al: Histamine-releasing potencies of atracurium, dimethyl-tubocurarine, and tubocurarine. Br J Anaesth 55:105S, 1983

11.

Savarese JJ , Ali HH , Basta SJ , et al: The cardiovascular effects of mivacurium chloride (BW B1090U) in patients receiving nitrous oxide-opiate-barbiturate anesthesia. Anesthesiology 90:386-394,1989

12.

Savarese JJ , Wastila WB : Current research in relaxant development . Semin Anaesth 5:304-311, 1986

13.

Stoops CM , Curtis CA , Kovach DA , et al: Hemodynamic effects of mivacurium chloride administered to patients during oxygen-sufentanil anesthesia for coronary artery bypass grafting or valve replacement. Anesth Analg 68:333, 1989

14.

Hatano Y. , Arai T. , Noda J. , et al: Contribution of prostacyclin to d-tubocurarine-induced hypotension in humans. Anesthesiology 72:28-32, 1990

15.

Moss J. , Rosow CE , Savarese JJ , et al: Role of histamine in the hypotensive action of d-tubocurarine in humans. Anesthesiology 55:19-25, 1981

16.

Scott Rpf , Savarese JJ , Basta SJ , et al: Clinical pharmacology of atracurium given in high dose. Br J Anaesth 58:834-838, 1986

17.

Basta SJ , Ali HH , Savarese JJ , et al: Clinical pharmacology of atracurium besylate (BW33A): A new non-depolarizing muscle relaxant. Anesth Analg 61:723-729, 1982

18.

Basta SJ , Savarese JJ , Ali HH , et al: Clinical pharmacology of doxacurium chloride: A new long-acting nondepolarizing muscle relaxant. Anesthesiology 69:478-486, 1988

19.

Murray DJ , Mehta MP , Choi WW , et al: The neuromuscular blocking and cardiovascular effects of doxacurium chloride in patients receiving nitrous oxide narcotic anesthesia. Anesthesiology 69:472-477, 1988

20.

Stoops CM , Curtis CA , Kovach DA , et al: Hemodynamic effects of doxacurium chloride in patients receiving oxygen-sufentanil anesthesia for coronary artery bypass or valve replacement . Anesthesiology 69:365-370, 1988

21.

Lien CA , Belmont MR , Abalos A. , et al: The cardiovascular effects and histamine-releasing properties of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia . Anesthesiology 82:1131-1138, 1995

22.

Scott Rpf , Savarese JJ , Basta SJ , et al: Atracurium: Clinical strategies for preventing histamine release and attenuating the hemodynamic response. Anesthesiology 61:A287, 1984

23.

Powers D. , Simpson K. , Morici M. , et al: The hemodynamic effects of mivacurium chloride in patients undergoing coronary artery bypass graft during fentanyl/valium anesthesia. Anesthesiology 69:A530, 1988

24.

Choi WW , Mehta MP , Murray DJ , et al: Neuromuscular and cardiovascular effects of mivacurium chloride in surgical patients receiving nitrous oxide-narcotic or nitrous oxide-isoflurane anaesthesia. Can J Anaesth 36:641-650, 1989

25.

From RP , Pearson KS , Choi WW , et al: Neuromuscular and cardiovascular effects of mivacurium chloride (BW B1090U) during nitrous oxide-fentanyl-thiopentane and nitrous oxide-halothane anaesthesia. Br J Anaesth 64:193-198, 1990

26.

Durant NN , Bowman WC , Marshall IG : A comparison of the neuromuscular and autonomic blocking activities of (+)-tubocurarine and its N-methyl and O,O,N-trimethyl analogues. Eur J Pharmacol 46:297-302, 1977

27.

Savarese JJ , Ali HH , Antonio RP : The clinical pharmacology of metocurine: Dimethyltubocurarine revisited. Anesthesiology 47:277-284, 1977

28.

Matteo RS , Brotherton WP , Nishitateno K. , et al: Pharmacodynamics and pharmacokinetics of metocurine in humans: Comparison to d-tubocurarine. Anesthesiology 57:183-190,1982

29.

Miller RD , Matteo RS , Benet LZ , Sohn YJ : The pharmacokinetics of tubocurarine in man with and without renal failure . J Pharmacol Exp Ther 202:1-7, 1977

30.

Stoelting RK : Hemodynamic effects of dimethyltubocurarine during nitrous oxide-halothane anesthesia. Anesth Analg 53:513-515, 1974

31.

Stoelting RK : The hemodynamic effects of pancuronium and d-tubocurarine in anesthetized patients. Anesthesiology 36:612-615, 1972

32.

Basta SJ , Savarese JJ , Ali HH , et al: Neuromuscular and cardiovascular effects in patients of BW A938U: A new long-acting neuromuscular blocking agent. Anesthesiology 65:A281, 1986

33.

Bowman WC , Rodger IW , Houston J. , et al: Structure: action relationships among some desacetoxy analogues of pancuronium and vecuronium in the anesthetized cat. Anesthesiology 69:57-86, 1988

34.

Kopman AF : Gallamine, pancuronium and d-tubocurarine compared: Is onset time related to drug potency? Anesthesiology 70:915-520, 1989

35.

Lien CA , Matteo RS , Ornstein E. , et al: Neostigmine antagonism of doxacurium or pancuronium blockade under isoflurane. Anesthesiology 77:A959, 1992

36.

Emmot RS , Bracey BJ , Goldhill DR , et al: Cardiovascular effects of doxacurium, pancuronium, and vecuronium in anesthetized patients presenting for coronary artery bypass surgery. Br J Anaesth 65:480-486, 1990

37.

Ali HH , Savarese JJ , Embree PB , et al: Clinical pharmacology of mivacurium chloride (BW B1090U) infusion: Comparison with vecuronium and atracurium. Br J Anaesth 61:541-546, 1988

38.

Engback J. , Ostergaard D. , Skovgaard LT , Viby-Mogensen J. : Reversal of intense neuromuscular blockade following infusion of atracurium . Anesthesiology 72:803-806, 1990

39.

Hosking MP , Lennon RL , Gronert GA : Combined H1and H2-receptor blockade attenuates the cardiovascular effects of high-dose atracurium for rapid sequence endotracheal intubation . Anesth Analg 67:1089-1093, 1988

40.

Scott Rpf , Savarese JJ , Basta SJ , et al: Atracurium: Clinical strategies for preventing histamine release and attenuating the hemodynamic response. Br J Anaesth 57:550-555, 1985

41.

Belmont MR , Lien CA , Quessy S. , et al: The clinical neuromuscular pharmacology of 51 W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia. Anesthesiology 82:1139-1145, 1995

42.

Fisher DM , Rosen JI : A pharmacokinetic explanation for increasing recovery time following larger or repeated doses of nondepolarizing muscle relaxants. Anesthesia 65:286-291, 1986

43.

Lien CA , Pavlin EG , Belmont MR , et al: A two-center study to evaluate cisatracurium (51W89) for tracheal intubation in patient recesing propofol or thiopental anesthesia. Anesthesia 53A223. 1995

44.

Schmautz E. Deriaz M. Volleo A. Lienhart A. : Evaluation of 51W89 for endotracheal mtubation in surgical patients during N2O O2 prupofol anesthesia. Anesthesia 81:A1081, 1994

45.

Stout RG , Belmont MR , Paviin EG , et al: Evaluation of intubation at 90 and 12 seconds following 51W89 administration. Anesthesiz SRA1078, 1994

46.

Kopman A. : Nondepoiarizing relaxants: New concepts and new drugs. J Clin Anessin 56 Suppl 1):395-455, 1993

47.

Meretoja OA , Taivainen T. Wirtavouri K. : Pharmacodynamic effects of 51WS9, an isomer of atracurium, in children during halotnane anaesthesia. Br J Anaesth 74:6-11, 1995

48.

Brandom BW , Woelfel SK Gronert BJ , et al: Effects of 51W89 (cisatracurium in children during halothane nitrous oxide anesthesia. Anesthesiology 83:A921, 1995

49.

Ornstein E. Lien CA Matteo RS et al: Pharmacodynamics and pharmacokinetics of 31W89 in geriatric surgical patients. Anesthesiology S1A1075, 1994

50.

Lien CA , Schmith VD , Belmont MR , et al: Pharmacokinetics of 51W89 in patients receiving nitrous oxide-opioid-barbiturate anesthesia. Anesthesiology 83:300-308, 1995

51.

Prielipp RC Coursin DB Scuderi PE , et al: Comparison of the infusion requiremems and recovery profiles of vecuronium and cisamcurium 51W89 in intensive care unit patients. Anesth Analg S1:3-12. 1995

52.

Reich DL , Konstadt SN Stanlev TE , et al: A two-center study of the cardiovascular effects of 51W89 in patients with coronary artery disease. Anesth Analg 80:S393, 1995

53.

Savarese JJ , Ali HH , Basta SJ et al: The clinical neuromuscular pharmacology of mivacurium chloride (BW B1090U): A short-acting nondepolarizing ester neuromuscular blocking drug. Anesthesiology 68:723-732, 1988

54.

Plaud B. , Legueau F. Debaene B , et al: Mivacurium neuromuscular blockade at the adductor muscles of the larynx and adductor pollicis in man. Anesthesiology 77:A908, 1992

55.

Cantineau JP , Parte F. Horns JB , et al: Neuromuscular blocking effect of ORG 9426 on human diaphragm. Anesthesiology 75:A785, 1991

56.

Donati F. : Onset of action of relaxants. Can J Anaesth 35:S52-S58, 1988

57.

Donati F. , Antzaka C. , Bevan DR : Potency of pancuronium at the diaphragm and adductor pollicis muscles in humans . Anesthesiology 65:1-5, 1986

58.

Donati F. , Plaud B. , Meistleman D. : Vecuronium neuromuscular blockade at the adductor muscles of the larynx and at the adductor pollicis. Anesthesiology 74:833-837, 1991

59.

Plaud B. , Meistleman C. , Donati F. : Organon 9426 neuromuscular blockade at the adductor muscles of the larynx and adductor pollicis in man. Anesthesiology 75:A784, 1991

60.

Ali HH , Brull SJ , Witkowski T. , et al: Efficacy and safety of divided-dose administration for rapid tracheal intubation. Anesthesiology 79:A934, 1993

61.

Stanley JC , Carson IW , Gibson FM , et al: Comparison of the haemodynamic effects of pipecuronium and pancuronium during fentanyl anaesthesia. Acta Anaesthesiol Scand 35:262-266, 1991

62.

Upton RA , Nguyen RL , Miller RD , et al: Renal and biliary elimination of vecuronium (ORG NC 45) and pancuronium in rats. Anesth Analg 61:313, 1982

63.

Starr NJ , Sethna DH , Estafanoous FG : Bradycardia and asystole following the rapid administration of sufentanil with vecuronium. Anesthesiology 64:521, 1986

64.

Bartkowski RR , Witkowski TA , Azad S. , et al: Rocuronium onset of action: A comparison with atracurium and vecuronium. Anesth Analg 77:574-578, 1993

65.

Vuksanaj D. , Fisher DM : Pharmacokinetics of rocuronium in children aged 4-11 years. Anesthesiology 82:1104-1110, 1995

66.

Matteo RS , Ornstein E. , Schwartz AE , et al: Pharmacokinetics and pharmacodynamics of rocuronium (Org 9426) in elderly surgical patients. Anesth Analg 77:1193-1197, 1993

67.

Khalil M. , D'Honneur G. , Duvaldestin P. , et al: Pharmacokinetics and pharmacodynamics of rocuronium in patients with cirrhosis. Anesthesiology 80:1241-1247, 1994

68.

Levy JH , Davis GK , Duggan J. , Szlam F. : Determination of the hemodynamics and histamine release of rocuronium (Org 9426) when administered in increased doses under N2O/O2-sufentanil anesthesia. Anesth Analg 78:318-321, 1994

69.

McCoy EP , Maddineni VR , Elliott P. , et al: Haemodynamic effects of rocuronium during fentanyl anaesthesia: comparison with vecuronium. Can J Anaesth 40:703-708, 1993