Many transmeridian travellers, including top athletes, regularly take melatonin to reduce negative jet lag symptoms. Standard (rather than individually tailored) doses are often used. We examined the effects of a standard dose of melatonin on the body temperature rhythms of 12 elite biathletes (eight men and four women) after an eastward transmeridian flight to an international competition. The different effects on body temperature rhythms in men versus women underscore the need for personalized dosing schedules to avoid potential undesirable consequences.
GraeberRC: Alterations in performance following rapid transmeridian flight. In: Rhythmic Aspects of Behaviour (BrownFMGraeberRC eds). Hillsdale: Lawrence Erlbaum Associates, 1982; pp 173–212
3.
BrzezinskiA: Melatonin in humans. N Engl J Med1997; 336: 186–195
4.
ReillyTAtkinsonGWaterhouseJ (eds): Physiological rhythms at rest. In: Biological Rhythms and Exercise.Oxford: Oxford University Press, 1997; pp15-27
5.
MojònAFernàndezJRHermidaRCChronolab: an interactive software package for chronobiologic time series analysis written for the Macintosh computer. Chronobiol Int1992; 9: 403–412
6.
HalbergFCarandenteFCornelissenG: Glossary of chronobiology. Chronobiologia1977; 4 (Suppl 1): 1–192
7.
AtkinsonGReillyT: Circadian variation in sports performance. Sports Med1996; 21: 292–312
8.
WingetCMSolimanMRIHolleyDC: Chronobiology of physical performance and sports medicine. In: Biologic Rhythms in Clinical and Laboratory Medicine (TouitouYHausE eds). Berlin and Heidelberg: Springer Verlag, 1992; pp 230–242
9.
RietveldWJ: Circadian rhythms: physical performance as function of the time of day. Int J Sports Med1984; 5: 25–27
10.
ShepardRJ: Sleep, biorhythms and human performance. Sports Med1984; 1: 11–37
11.
WingetCMDeRoshiaCWHolleyDC: Circadian rhythms and athletic performance. Med Sci Sports Exerc1985; 17: 498–516
12.
ReillyT: Human circadian rhythms and exercise. Crit Rev Biomed Eng1990; 18: 165–180
13.
YoungstedtSDO'ConnorPJ: The influence of air travel on athletic performance. Sports Med1999; 28: 197–207
14.
ReillyTMaughanRBudgettR: Melatonin: a position statement of the British Olympic Association. Br J Sports Med1998; 32: 99–100