A new coumarin with a ferulic acid moiety (1), together with three known coumarins, viz. isoscopletin-6-O-β-D-glucopyranoside (2), elebutheroside B1 (3), tert-O-β-D-glucopyranosyl-(R)-heraclenol (4), were isolated from the roots of Heracleum dissectum. Their structures were clarified by extensive spectroscopic data analysis including 1D and 2D NMR and HRESI MS and comparison with previous literatures (known compounds). Moreover, the absolute configuration of the new compound was also determined.
MiJ, PengYJ, ZhangHM, WangXR, HuoYY, WangZG, LiuY, GaoY, ZhangHL. (2018) A new benzofuran derivative glycoside and a new coumarin glycoside from roots of Heracleum dissectum Ledeb. Medicinal Chemistry Research, 27, 470–475.
2.
XinXJ, LiuCX and LiYC. (2016) Cultivation techniques of wild vegetable Heracleum dissectum in Daxinganling. Protection Forest Science and Technology, 120–121.
3.
PapageorgiouVP, OchirG, MotlO, ArgyriadouN, DunkelH. (1985) Composition of the essential oil from Heracleum dissectum. Journal of Natural Products, 48, 851–853.
4.
BenesovaV. (1962) Plant substances .20. Constituents of Heracleum dissectum L. Root. Collection of Czechoslovak Chemical Communications, 27, 2714–2716.
5.
GaoY, LiuY, WangZG, ZhangHL. (2014) Chemical constituents of Heracleum dissectum and their cytotoxic activity. Phytochemistry Letters, 10, 276–280.
6.
ZhangHL, WuXY, MiJ, PengYJ, WangZG, LiuY, WuXL, GaoY. (2017) A new anti-inflammatory alkaloid from roots of Heracleum dissectum. Chemistry and Biodiversity, 14, e-1700184, 1–5.
7.
JiaXD, ZhaoXZ, FengX, WangM, SunH, DongYF. (2008) Coumarins of Angelica dahurica var. formosana (II). Chinese Traditional and Herbal Drugs, 39, 1768–1771.
8.
LiB, ZhangDM, LuoYM. (2006) Chemical constituents from root of Lasianthus acuminatissimus I. China Journal of Chinese Materia Medica, 31, 133–135.
9.
KozawaM, MatsuyamaY, FukumotoM, BabaK. (1983) Chemical studies of Coelopleurum gmelinii (D.C.) LEDEB. I. Constituents of the root. Chemical & Pharmaceutical Bulletin, 31, 64–69.
