We report a case of chronic recurrent multifocal osteomyelitis in a 9-year-old girl. She presented with a 9-month history of gradually worsening pain and swelling in her left foot. Non-steroidal anti-inflammatory drugs were prescribed but the symptoms persisted. She underwent curettage through a small oval corticotomy window on the first metatarsal bone. The pain and swelling improved promptly and she was able to walk without pain 2 weeks later. Curettage enabled rapid symptomatic relief and induced remission, with little risk of complications.
MollanRACraigBFBiggartJD. Chronic sclerosing osteomyelitis. An unusual case. J Bone Joint Surg Br1984;66:583–5.
2.
LissensMBruyninckxFRosselleN. Condensing osteitis of the clavicle. Report of two cases and review of the literature. Acta Belg Med Phys1990;13:235–40.
3.
AppellRGOppermannHCBeckerWKratzatRBrandeisWEWillichE. Condensing osteitis of the clavicle in childhood: A rare sclerotic bone lesion. Review of literature and report of seven patients. Pediatr Radiol1983;13:301–6.
4.
JurikAGMollerSHMosekildeL. Chronic sclerosing osteomyelitis of the iliac bone. Etiological possibilities. Skeletal Radiol1988;17:114–8.
5.
Viejo-FuertesDRossillonRMousnyMDocquierPLLecouvetFRomboutsJJ. Primary chronic sclerosing osteomyelitis–a case-report. Joint Bone Spine2005;72:73–5.
6.
HuauxJPEsselinckxWRomboutsJJMaldagueBMalghemJDevogelaerJP. Pustulotic arthroosteitis and chronic recurrent multifocal osteomyelitis in children. Report of three cases. J Rheumatol1988;15:95–100.
GirschickHJKrauspeRTschammlerAHuppertzHI. Chronic recurrent osteomyelitis with clavicular involvement in children: Diagnostic value of different imaging techniques and therapy with non-steroidal anti-inflammatory drugs. Eur J Pediatr1998;157:28–33.
9.
Beretta-PiccoliBCSauvainMJGalISchiblerASaurenmannTKressebuchH. Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome in childhood: A report of ten cases and review of the literature. Eur J Pediatr2000;159:594–601.
10.
ProbstFPBjorkstenBGustavsonKH. Radiological aspect of chronic recurrent multifocal osteomyelitis. Ann Radiol (Paris)1978;21:115–25.
11.
SolheimLFPausBLiverudKStoenE. Chronic recurrent multifocal osteomyelitis. A new clinical-radiological syndrome. Acta Orthop Scand1980;51:37–41.
12.
TyrrellPNCassar-PullicinoVNEisensteinSMMonachJFDarbyAJMcCallIW. Back pain in childhood. Ann Rheum Dis1996;55:789–93.
HuberAMLamPYDuffyCMYeungRSDitchfieldMLaxerD. Chronic recurrent multifocal osteomyelitis: Clinical outcomes after more than five years of follow-up. J Pediatr2002;141:198–203.
15.
GirschickHJRaabPSurbaumSTrusenAKirschnerSSchneiderP. Chronic non-bacterial osteomyelitis in children. Ann Rheum Dis2005;64:279–85.
El-ShantiHIFergusonPJ. Chronic recurrent multifocal osteomyelitis: A concise review and genetic update. Clin Orthop Relat Res2007;462:11–9.
18.
BjorkstenBBoquistL. Histopathological aspects of chronic recurrent multifocal osteomyelitis. J Bone Joint Surg Br1980;62:376–80.
19.
GirschickHJHuppertzHIHarmsenDKrauspeRMuller-HermelinkHKPapadopoulosT. Chronic recurrent multifocal osteomyelitis in children: Diagnostic value of histopathology and microbial testing. Hum Pathol1999;30:59–65.
JanssonARennerEDRamserJMayerAHabanMMeindlA. Classification of non-bacterial osteitis: Retrospective study of clinical, immunological and genetic aspects in 89 patients. Rheumatology (Oxford)2007;46:154–60.
22.
BergdahlKBjorkstenBGustavsonKHLidenSProbstF. Pustulosis palmoplantaris and its relation to chronic recurrent multifocal osteomyelitis. Dermatologica1979;159:37–45.
23.
SimmPJAllenRCZacharinMR. Bisphosphonate treatment in chronic recurrent multifocal osteomyelitis. J Pediatr2008;152:571–5.
24.
GallagherKTRobertsRLMacFarlaneJAStiehmER. Treatment of chronic recurrent multifocal osteomyelitis with interferon gamma. J Pediatr1997;131:470–2.
25.
DeutschmannAMacheCJBodoKZebedinDRingE. Successful treatment of chronic recurrent multifocal osteomyelitis with tumor necrosis factor-alpha blockage. Pediatrics2005;116:1231–3.
