Both ovarian malignancy and gonadal dysgenesis in the adolescent period are rare. Ovarian tumors represent approximately 1% of childhood malignancies. Gonadal dysgenesis is also unusual and results when the germ cells are lacking and the ovary is replaced by a fibrous streak. An 18-year-old with primary amenorrhea,acute pelvic pain,and a 16-cm pelvic mass was found to have both a malignant mixed germ cell tumor and a contralateral streak ovary.
Kurman RJ ,Norris HJ: Malignant mixed germ cell tumors of the ovary: a clinical and pathologic analysis of 30 cases. Obstet Gynecol1976;48:579-579.
2.
Simpson JL : Gonadal dysgenesis and abnormalities of the human sex chromosomes: current status of phenotypickaryotypic correlations. Birth Defects1975;11:23–59.
3.
Simpson JL : Genetic forms of gonadal dysgenesis in 46,XY individuals. Semin Reprod Endocrinol1983;1:93–100.
4.
Wilson EE ,Vuitch F,Carr BR: Laparoscopic removal of dysgenetic gonads containing a gonadoblastoma in a patient with Swyer's syndrome. Obstet Gynecol1992;79:842–844.
5.
Davidoff F ,Federman DD: Mixed gonadal dysgenesis. Pediatrics1973;52:725–742.
6.
Mendes JR ,Strufaldi MW,Delcelo R,et al: Y-chromosome identification by PCR and gonadal histopathology in Turner's syndrome without overt Y mosaicism. Clin Endocrinol1999;50:19–26.
7.
Krasna IH ,Lee M,Smillow P,Sciorra L,Eierman L: Risk of malignancy in bilateral streak gonads: the role of the Y chromosome. J Pediatr Surg1992;27:1376–1380.
8.
Chy C : Y-chromosome mosaicism in girls with Turner's syndrome. Clin Endocrinol1999;50:17–18.
9.
Novak AZ ,Kokai GK,Popovic VP,Ludoski MD,Jurokovski VA: Interphase cytogenetics on paraffin-embedded sections of ovary for detection of genomic constitution in a patient with Turner's syndrome and chromosomal mosaicism. Hum Genet1995;95:293–298.
10.
Shy K : Is color Doppler ultrasound useful in diagnosing ovarian cancer?Clin Obstet Gynecol1999;42:902–915.
