Abstract

Purpose: NINDS invites applications for Center Core Grants to support neuroscience research. The purpose of this program is to advance the NINDS mission to promote the understanding and treatment of neurological disorders by providing core research facilities that are not otherwise available. Each Center Core Grant will support shared resources and facilities used by investigators with research projects funded by NINDS. This support, by providing more accessible resources, is expected to ensure greater productivity than would be possible in separate projects. An institution is eligible for a maximum of one NINDS Center Core Grant. These awards will support basic, translational, and clinical research but will not be used to support clinical trials or to provide patient services.
Term/Amount: This PA will use the NIH Center Core Grants (P30) award mechanism. Applicants will be solely responsible for planning, directing, and executing the proposed project. Applicants may request up to $500,000 per year in direct costs. The total project period for an application submitted in response to this PA may not exceed 5 years. This PA uses just-in-time concepts. The NIH Grants Policy Statement and applicable cost principles govern allowable costs. Specific limits as well as certain items that may be requested are delineated in the full on-line version of this PA at http://grants.nih.gov/grants/guide/pa-files/PAR-02-059.html. Salary support for the PI may not exceed 5% effort. Support for secretarial and administrative staff may be requested to the extent that it relates directly to the management of the Center. Costs for PI salary and support for secretarial and administrative staff may not exceed 15% of the total direct costs for a Center in any year. Salary may not be requested for PIs of qualifying projects or directors of individual cores within the Center. Salary may be requested for technical support personnel and consultants. Requests for shared equipment are allowed. Consumable supplies may be requested to the extent that they are directly related to the operation of the cores. These supplies should be generic in nature and used for purposes that are not project-specific. Unique research reagents and supplies that are specific to the support of individual projects, including experimental animals, may not be requested. Costs for animal purchase and care are not allowed, except in animal model cores. Travel costs are not allowed. Patient care and recruitment costs are not allowed. Costs for seminars and workshops are not allowed. Alteration and renovation costs are not allowed.
Special Requirements with Regard to Human Embryonic Stem Cells (hESCs): Criteria for federal funding of research on hESCs can be found at http://grants.nih.gov/grants/stem_cells.htm and at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-005.html. Only research using hESC lines that are registered in the NIH Human Embryonic Stem Cell Registry will be eligible for federal funding (see http://escr.nih.gov). It is the responsibility of the applicant to provide the official NIH identifiers for the hESC lines to be used in the proposed research. Applications that do not provide this information will be returned without review.
Contact: Signed, typewritten original of the application, including the checklist and four signed photocopies in one package, to: Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 1040, MSC 7710, Bethesda, MD 20892-7710 (use ZIP code 20817 for express/courier service). Simultaneously, to facilitate the review of applications, the applicant should mail or deliver one copy of the application to: Lillian Pubols, PhD, Chief, Scientific Review Branch, National Institute of Neurological Disorders and Stroke, 6001 Executive Boulevard, Room 3208, Bethesda, MD 20892 (use ZIP code 20852 for express/courier service). Applications must be prepared using the PHS 398 research grant application instructions and forms (Rev. 5/2001). The PHS 398 is available at http://grants.nih.gov/grants/funding/phs398/phs398.html in an interactive format. For further assistance, contact GrantsInfo: telephone (301) 435-0714, email:
Deadlines: Applications submitted in response to this PA will be accepted at the standard application deadlines, which are available at http://grants.nih.gov/grants/dates.htm and/or at http://grants.nih.gov/grants/funding/submissionschedule.htm. Application deadlines are indicated in the PHS 398 application kit as well. This PA expires on February 28, 2005, unless it is reissued.
