Eosinopenia Due to Glucose Administration. ∗

Summary

1. The absolute eosinophile count in the dog varies markedly from animal to animal. The variability of the eosinophile count in the dog is reflected by a mean adjusted coefficient of variation of ± 11.1%.

2. Hyperglycemia produced by the oral or intravenous administration of glucose in the unanesthetized dog causes an eosinopenic response presumably mediated through activation of the pituitary-adrenal mechanism. In this respect hyperglycemia may be construed as a non-specific stress factor.