Creatinine and creatin metabolism in dogs with Eck fistula

In connection with certain studies of hepatic function the creatin and creatinine metabolism were investigated in two dogs with Eck fistula. This subject was studied last year by London and Boljarski. 1 They found that the administration of creatinine did not increase urinary creatinine, and that the feeding of creatin caused no increase in creatin excretion but was followed by a slight increase in eliminated creatinine.

The diet given our dogs consisted of unsweetened condensed milk, cracker meal, lard and water. Dog I took food with no apparent hunger and would at no time eat the prescribed amount, some days taking scarcely any. To this, in part is to be assigned the rapid loss in weight. Dog II took his food well and maintained constant weight. 2