Do Soy Sterols Interfere with Absorption of Cholesterol?

Summary

1. The effect of soy sterols upon recoveries of digitonin-precipitable C¹⁴ in thoracic duct lymph of rats fed C¹⁴-labeled cholesterol was studied. That administered soy sterols depress cholesterol absorption is fully confirmed, when as little as 4 mg or as much as 100 mg of cholesterol were fed. 2. The validity of absorption studies for cholesterol based on the amounts of digitonin-precipitable, Liebermann-Burchard positive materials recovered in lymph is discussed.