Effect of Dietary Factors on Incidence of “Spontaneous” and Induced Convulsions in C 3 H Male Mice. ∗

Summary

1. The incidence of “spontaneous” convulsions and of convulsive deaths in C₃H male mice is greatly reduced by caloric restriction or by supplement of vit. B₁₂ in the diet fed ad libitum. Substitution of hydrogenated vegetable fat for lard decreased the age of onset of convulsions and increased the incidence of convulsive deaths. 2. Studies with auditory and electric stimulation appear to confirm the existence of a difference between the effect of HVF and of lard.