By means of EEG analysis the functional state of subjects with high and low levels of anxiety was studied in different periods preceding a cognitive task – a visual expression recognition. Several conditions were investigated: background/eyes closed; background/eyes opened; listening the instruction for the cognitive task; operative rest (time lapse between listening the instruction and the beginning of the task), as well as short intervals immediately preceding the exposition of target stimuli (stage of preparation) – pairs of faces pictures with identical or different emotional expressions. At all these pre-task stages high-anxiety subjects exhibited much lower amplitude values in alpha and theta bands (as compared with low-anxiety subjects). The most prominent differences were revealed in the phases of instruction listening and operative rest. These data could provide more precise electrophysiological markers of anxiety level in conditions preceeding cognitive task performance.
AftanasL.I., KoshkarovV.I., PokrovskajaV.L., LotovaN.V. and MordvintsevY.N., Pre- and post-stimulus processes in affective task and event-related desynchronization: Do they discriminate anxiety coping styles?, Int. J. Psychophysiol.24 (1996), 197–212. doi:10.1016/S0167-8760(96)00060-8.
2.
BlackmonK., BarrW.B., CarlsonC., DevinskyO., DuboisJ., PogashD., QuinnB.T., KuznieckyR., HalgrenE. and ThesenT., Structural evidence for involvement of a left amygdala-orbitofrontal network in subclinical anxiety, Psychiatry Res.194 (2011), 296–303. doi:10.1016/j.pscychresns.2011.05.007.
3.
BlairK.S., GeraciM., SmithB.W., HollonN., DeVidoJ., OteroM., BlairJ.R. and PineD.S., Reduced dorsal anterior cingulate cortical activity during emotional regulation and top-down attentional control in Generalized Social Phobia (GSP), Generalized Anxiety Disorder (GAD) and comorbid GSP/GAD, Biol. Psychiatry72 (2012), 476–482. doi:10.1016/j.biopsych.2012.04.013.
4.
BlairR.J.R. and CipolottiL., Impaired social response reversal. A case of ‘acquired sociopathy’, Brain123 (2000), 1122–1141. doi:10.1093/brain/123.6.1122.
5.
BollingerJ., RubensM.T., ZantoT.P. and GazzaleyA., Expectation-driven changes in cortical functional connectivity influence working-memory and long-term memory performance, J. Neurosci.30 (2010), 14399–14410. doi:10.1523/JNEUROSCI.1547-10.2010.
6.
BussK.A., SchumacherJ.R., DolskiI., KalinN.H., GoldsmithH.H. and DavidsonR.J., Right frontal brain activity, cortisol, and withdrawal behavior in 6-month-old infants, Behav. Neurosci.117 (2003), 11–20. doi:10.1037/0735-7044.117.1.11.
7.
CislerJ.M., JamesG.A., TripathiS., MletzkoT., HeimC., HuX.P.et al., Differential functional connectivity within an emotion regulation neural network among individuals resilient and susceptible to the depressogenic effects of early life stress, Psychol. Med.43 (2013), 507–518. doi:10.1017/S0033291712001390.
8.
CoanJ.B. and AllenJ.A., Frontal EEG asymmetry as a moderator and mediator of emotion, Psychology67 (2004), 7–49.
9.
CooperN.R., CroftR.J., DomineyS.J.J., BurgessA.P. and GruzelierJ.H., Paradox lost? Exploring the role of alpha oscillationsduring externally vs. internally directed attention and the implications for idling and inhibition hypotheses, Int. J. Psychophysiol.47 (2003), 65–74. doi:10.1016/S0167-8760(02)00107-1.
10.
CrawfordH., KnebelT., VendemiaJ., KaplanL. and RatcliffB., EEG activation patterns during tracking and decision-making tasks: Differences between low and high sustained attention, in: Eighth International Symposium on Aviation Psychology, 1995.
11.
DavidsonR.J., Anxiety and affective style: Role of prefrontal cortex and amygdale, Biol. Psychiatry51 (2002), 68–80. doi:10.1016/S0006-3223(01)01328-2.
12.
DavidsonR.J. and SuttonS.K., Affective neuroscience: The emergence of a discipline, Current Opin. Neurobiol.5 (1995), 217–225.
13.
DesimoneR. and DuncanJ., Neural mechanisms of selective visual attention, Annu. Rev. Neurosci.18 (1995), 193–222. doi:10.1146/annurev.ne.18.030195.001205.
14.
EtkinA., PraterK.E., HoeftF., MenonV. and SchatzbergA.F., Failure of anterior cingulate activation and connectivity with the amygdala during implicit regulation of emotional processing in generalized anxiety disorder, Am. J. Psychiatry167 (2010), 545–554. doi:10.1176/appi.ajp.2009.09070931.
15.
FarberD.A., MachinskayaR.I., KurganskiiA.V. and PetrenkoN.E., Functional organization of the brain during preparation for recognition of image fragments, Neuroscience and Behavioral Physiology45 (2015), 1055–1062. doi:10.1007/s11055-015-0185-6.
16.
FellJ., LudowigE., StaresinaB.P., WagnerT., KranzT., ElgerC.E. and AxmacherN., Medial temporal theta/alpha power enhancement precedes successful memory encoding: Evidence based on intracranial EEG, J. Neurosci.31 (2011), 5392–5397. doi:10.1523/JNEUROSCI.3668-10.2011.
17.
GarnerM., BaldwinD., BradleyB. and MoggK., Impaired identification of fearful faces in Generalised Social Phobia, J. Affective Disorders115 (2009), 460–465. doi:10.1016/j.jad.2008.10.020.
18.
GordeevS.A., KovrovG.V., PosokhovS.I. and KatyenkoS.V., Psychophysiological characteristics of nonepileptic paroxysmal disorders, Neuroscience and Behavioral Physiology45 (2015), 375–383. doi:10.1007/s11055-015-0085-9.
19.
GrayJ.A. and McNaughtonN., The Neuropsychology of Anxiety: An Enquiry Into the Functions of the Septohippocampal System, 2nd edn, Oxford University Press, Oxford, 2000.
20.
GuderianS., SchottB.H., Richardson-KlavehnA. and DüzelE., Medial temporal theta state before an event predicts episodic encoding success in humans, Proc. Natl. Acad. Sci. U. S. A.106 (2009), 5365–5370. doi:10.1073/pnas.0900289106.
21.
GyurakA., GrossJ.J. and EtkinA., Explicit and implicit emotion regulation: A dual-process framework, Cogn. Emot.25 (2011), 400–412. doi:10.1080/02699931.2010.544160.
22.
HagemannJ., StraubeT. and SchulzC., Too bad: Bias for angry faces in social anxiety interferes with identity processing, Neuropsychologia.84 (2016), 136–149. doi:10.1016/j.neuropsychologia.2016.02.005.
23.
HsiehL.T. and RanganathC., Frontal midline theta oscillations during working memory, Neuroimage85 (2014), 721–729. doi:10.1016/j.neuroimage.2013.08.003.
24.
KalinN.H., SheltonS.E. and DavidsonR.J., Cerebrospinal fluid corticotropin-releasing hormone levels are elevated in monkeys with patterns of brain activity associated with fearful temperament, Biol. Psychiatry47 (2000), 79–85.
25.
KesslerR.C., Aguilar-GaxiolaS., AlonsoJ.et al., The global burden of mental disorders: An update from the WHO World Mental Health (WMH) surveys, Epidemiol. Psichiatry Soc.18 (2009), 23–33. doi:10.1017/S1121189X00001421.
26.
KillgoreW.D.S. and Yurgelun-ToddD.A., Activation of the amygdala and anterior cingulate during non-conscious processing of sad versus happy faces, Neuroimage21 (2004), 1215–1223. doi:10.1016/j.neuroimage.2003.12.033.
27.
KimM.J., GeeD.G., LoucksR.A., DavisF.C. and WhalenP.J., Anxiety dissociates dorsal and ventral medial prefrontal cortex functional connectivity with the amygdala at rest, Cereb. Cortex21 (2011), 1667–1673. doi:10.1093/cercor/bhq237.
28.
KlebergF.I., KitajoK., KawasakiM. and YamaguchiY., Ongoing theta oscillations predict encoding of subjective memory type, Neurosci. Res.83 (2014), 69–80. doi:10.1016/j.neures.2014.02.010.
29.
KnyazevG.G., LevinE.A. and SavostyanovA.N., Impulsivity, anxiety, and individual differences in evoked and induced brain oscillations, Int. J. Psychophysiol.68 (2008), 242–254. doi:10.1016/j.ijpsycho.2008.02.010.
30.
KnyazevG.G., SavostyanovA.N., BocharovA.V. and RimarevaJ.M., Anxiety, depression, and oscillatory dynamics in a social interaction model, Brain Research1644 (2016), 62–69. doi:10.1016/j.brainres.2016.04.075.
31.
KostandovE.A., The role of implicite estimation of time intervals and set plasticity in facial expression processing, Cognitive Systems Monographs25 (2015), 349–366. doi:10.1007/978-3-319-19446-2_21.
32.
KostandovE.A. and CheremushkinE.A., Influences of the loading on working memory on the spatial synchronization of prestimulus cortical electrical activity during recognition of an emotional facial expression, Neuroscience and Behavioral Physiology41 (2011), 591–598. doi:10.1007/s11055-011-9460-3.
33.
KostandovE.A., CheremushkinE.A., YakovenkoI.A. and PetrenkoN.E., Induced synchronization of the alpha rhythm during the pauses between visual stimuli with different levels of cognitive set plasticity, Neuroscience and Behavioral Physiology45 (2015), 154–163. doi:10.1007/s11055-015-0053-4.
34.
KostandovE.A., FarberD.A., CheremushkinE.A., PetrenkoN.E. and AshkinaziM.L., Spatial synchronization of the θ and α band cortical electrical oscillations in the formation of a set to an angry face expression in 5- to 11-year-old children, Human Physiology37 (2011), 519–525. doi:10.1134/S0362119711050082.
35.
KostandovE.A., FarberD.A., MachinskayaR.I., CheremushkinE.A., PetrenkoN.E. and AshkinaziM.L., Spatial synchronization of cortical electrical activity at different stages of a visual set in 8-year-old children with different levels of development of the frontothalamic selective attention system, Neuroscience and Behavioral Physiology41 (2011), 329–335. doi:10.1007/s11055-011-9420-y.
36.
KostandovE.A., KurovaN.S., CheremushkinE.A. and PetrenkoN.E., Dynamics of the spatial organization of cortical electrical activity during the formation and actualization of a cognitive set to facial expression, Neuroscience and Behavioral Physiology38 (2008), 15–22. doi:10.1007/s11055-008-0002-6.
37.
KurovaN.S. and CheremushkinE.A., Spectral EEG characteristics during increases in the complexity of the context of cognitive activity, Neuroscience and Behavioral Physiology37 (2007), 379–385. doi:10.1007/s11055-007-0024-5.
38.
LangeneckerS.A., BieliauskasL.A., RapportL.J., ZubietaJ.K., WildeE.A. and BerentS., Face emotion perception and executive functioning deficits in depression, Journal of Clinical and Experimental Neuropsychology27 (2005), 320–333. doi:10.1080/13803390490490515720.
39.
LegaB.C., JacobJ. and KahanaM., Human hippocampal theta oscillations and the formation of episodic memories, Hippocampus22 (2012), 748–761. doi:10.1002/hipo.20937.
40.
MahmoudJ.S.R., The Relationship of Anxiety, Coping, Thinking Style, Life Satisfaction, Social Support and Selected Demographics Among Young Adult College Students, University of Kentucky Doctoral Dissertations, 2011.
41.
MathersulD., WilliamsL.M., HopkinsonP.J. and KempA.H., Investigating models of effect: Relationship among EEG alpha asymmetry depression and anxiety, Emotion8 (2008), 560–572. doi:10.1037/a0012811.
MinB.K., KimS.J., ParkJ.Y. and ParkH.J., Prestimulus top-down reflection of obsessive-compulsive disorder in EEG frontal theta and occipital alpha oscillations, Neurosci. Lett.496 (2011), 181–185. doi:10.1016/j.neulet.2011.04.018.
44.
MoggK., MillarN. and BradleyB.P., Biases in eye movements to threatening facial expressions in generalized anxiety disorder and depressive disorder, J. Abnorm. Psychol.109 (2000), 695–704. doi:10.1037/0021-843X.109.4.695.
45.
MuellerE.M., HofmannS.G., SantessoD.L., MeuretA.E., BitranS. and PizzagalliD.A., Electrophysiological evidence of attentional biases in social anxiety disorder, Psychol. Med.39 (2009), 1141–1152. doi:10.1017/S0033291708004820.
46.
NyhusE. and CurranT., Functional role of gamma and theta oscillations in episodic memory, Neurosci. Biobeh. Rev.34 (2010), 1023–1035. doi:10.1016/j.neubiorev.2009.12.014.
47.
PalvaS., KulashekharS., HamalainenM. and PalvaJ.M., Localization of cortical phase and amplitude dynamics during visual working memory encoding and retention, J. Neurosci.31 (2011), 5013–5025. doi:10.1523/JNEUROSCI.5592-10.2011.
48.
PattenT.M., RennieC.J., RobinsonP.A. and GongP., Human cortical traveling waves: Dynamical properties and correlations with responses, PLoS One.7 (2012), e38392. doi:10.1371/journal.pone.0038392.
49.
PhanK.L., WagerT., TaylorS.F. and LiberzonI., Functional neuroanatomy of emotion: A meta-analysis of emotion activation studies in PET and fMRI, Neuroimage16 (2002), 331–348. doi:10.1006/nimg.2002.1087.
50.
PutmanP., Resting state EEG delta–beta coherence in relation to anxiety, behavioral inhibition, and selective attentional processing of threatening stimuli, International Journal of Psychophysiology80 (2011), 63–68. doi:10.1016/j.ijpsycho.2011.01.011.
51.
ScheeringaR., PeterssonK.M., OostenveldR., NorrisD.G., HagoortP. and BastiaansenM.C., Trial-by-trial coupling between EEG and BOLD identifies networks related to alpha and theta EEG power increases during working memory maintenance, Neuroimage44 (2009), 1224–1238. doi:10.1016/j.neuroimage.2008.08.041.
52.
SchutterD.J.L.G., van HonkJ., d'AlfonsoA.A.L., PostmaA. and de HaanE.H.F., Effects of slow rTMS at the right dorsolateral prefrontal cortex on EEG asymmetry and mood, NeuroReport12 (2001), 445–447. doi:10.1097/00001756-200103050-00005.
53.
ShangJ., FuY., RenZ., ZhangT., DuM., GongQ., LuiS. and ZhangW., The common traits of the ACC and PFC in anxiety disorders in the DSM-5: Meta-analysis of voxelbased morphometry studies, PLoS One9 (2014), e93432. doi:10.1371/journal.pone.0093432.
54.
SpampinatoM.V., WoodJ.N., De SimoneV. and GrafmanJ., Neural correlates of anxiety in healthy volunteers: A voxel-based morphometry study, J. Neuropsychiatry Clin. Neurosci.21 (2009), 199–205. doi:10.1176/jnp.2009.21.2.199.
55.
StuhrmannA., SuslowT. and DannlowskiU., Facial emotion processing in major depression: A systematic review of neuroimaging findings, Biology of Mood and Anxiety Disorders1 (2011), 10. doi:10.1186/2045-5380-1-10.
56.
Tallon-BaudryC., BertrandO., PeronnetF. and PernierJ., Indused gamma_band activity during the delay of a visual short_term memory task in humans, J. Neurosci.18 (1998), 4244–4254.
57.
TianX., WeD., DuX., WangK., YangJ.et al., Assessment of trait anxiety and prediction of changes in state anxiety using functional brain imaging: A test–retest study, Neuroimage133 (2016), 408–416. doi:10.1016/j.neuroimage.2016.03.024.
58.
Van den BulkB., MeensP., van LangN., de VoogdE., van der WeeN. and RomboutsS., Amygdala activation during emotional face processing in adolescents with affective disorder s: The role of underlying depression and anxiety symptoms, Frontiers in Human Neuroscience8 (2014), 1–13.
59.
Van DijkH., SchoffelenJ.M., OostenveldR. and JensenO., Prestimulus oscillatory activity in the alpha band predicts visual discrimination ability, J. Neurosci.28 (2008), 1816–1826. doi:10.1523/JNEUROSCI.1853-07.2008.
60.
Von SteinA., ChiangC. and KonigP., Top-down processing mediated by interareal synchronization, Proc. Natl. Acad. Sci. U. S. A.97 (2000), 14748–14753. doi:10.1073/pnas.97.26.14748.
61.
WangC., UlbertI., SchomerD.L., MarinkovicK. and HalgrenE., Responses of human anterior cingulate cortex microdomains to error detection, conflict monitoring, stimulus–response mapping, familiarity, and orienting, J. Neurosci.25 (2005), 604–613. doi:10.1523/JNEUROSCI.4151-04.2005.
62.
XingM., TadayonnejadR., MacNamaraA., AjiloreO., DiGangiJ., Luan PhanK., LeowA. and KlumppH., Resting-state theta band connectivity and graph analysis in generalized social anxiety disorder, NeuroImage: Clinical13 (2017), 24–32. doi:10.1016/j.nicl.2016.11.009.
63.
YamagishiN., CallanD.E., AndersonS.J. and KawatoM., Attentional changes in pre-stimulus oscillatory activity within early visual cortex are predictive of human visual performance, Brain Res.1197 (2008), 115–124. doi:10.1016/j.brainres.2007.12.063.
64.
ZhangY., WangX., BresslerS.L., ChenY. and DingM., Prestimulus cortical activity is correlated with speed of visuomotor processing, J. Cogn. Neurosci.20 (2008), 1915–1925. doi:10.1162/jocn.2008.20132.
