Adverse drug reactions reporting in children

The mission statement of the TEDDY project is to promote the research on the safe and effective use of drugs in children and to expand and integrate the knowledge and to build research capacity in the drug development for children.

One of the activities of WP1 – pharmacoepidemiology was to study the frequency and type of ADR reporting in children. For this analysis, we used data from the Uppsala Monitoring Centre (WHO collaborating Centre for International Drug Monitoring). All reports on ADRs in children (< 18 years), sent to the monitoring centre between 2000 and 2004 were analysed.

This report contains the first results on the ADR reporting in children. Within this report, we mainly focus on the occurrence of ADRs with a fatal outcome. In further analysis, we will further explore the association between causal related deaths and the use of specific drugs.