Abstract
Washington University School of Medicine in St. Louis (WUSM) researchers presented data recently showing that MRI brain scans using diffusion tensor imaging (DTI) perform better than common clinical tests, such as those for the APOE4 gene, at predicting which people will go on to develop Alzheimer’s disease. “Alzheimer’s disease is the most common cause of dementia in the world and is expected to increase globally, and especially in the U.S., as the population gets older,” explained lead study investigator Cyrus Raji, M.D., Ph.D., assistant professor of radiology at the Mallinckrodt Institute of Radiology at WUSM. “As we develop new drug therapies and study them in trials, we need to identify individuals who will benefit from these drugs earlier in the course of the disease.”.
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