Abstract
Dopamine antagonists including phenothiazines (e.g. chlorpromazine), metoclopramide and domperidone are also recognised causes of amenorrhoea. Physiologically, dopamine acts as a prolactin inhibitor so antagonism by medication may induce hyperprolactinaemia. The newer ‘atypical’ anti-psychotics such as olanzapine and quetiapine are less likely to have an effect on prolactin levels.
[InnovAiT Article: Amenorrhoea]