AKT answer relating to mental health and smoking

Answer A. Monitor closely and consider 25% dose increase

Smoking increases metabolism of many psychotropic medications and upon smoking cessation, doses may require immediate dose reduction to prevent medication toxicity. If smoking is resumed, original doses need to be reinstated. For escitalopram, monitor closely and consider 25% dose reduction.

InnovAiT article: Smoking and mental health conditions: What you need to know. DOI: 10.1177/17557380231185161.